Prognostic value of bone marrow histology in chronic lymphocytic leukemia. A study of 335 untreated cases from a single institution

University La Sapienza of Rome, Human Biopathology Dept., Italy. BACKGROUND AND METHODS. A significant correlation between bone marrow (BM) histology, survival and disease progression (DP) probability has been observed by several authors in chronic lymphocytic leukemia (CLL). The prognostic value of...

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Published in:Haematologica (Roma) 1994-07, Vol.79 (4), p.334-341
Main Authors: Mauro, FR, De Rossi, G, Burgio, VL, Caruso, R, Giannarelli, D, Monarca, B, Romani, C, Baroni, CD, Mandelli, F
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Bone Marrow Examination
Female
Follow-Up Studies
Humans
Leukemia, Lymphocytic, Chronic, B-Cell - pathology
Male
Middle Aged
Prognosis
Retrospective Studies
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Summary:University La Sapienza of Rome, Human Biopathology Dept., Italy. BACKGROUND AND METHODS. A significant correlation between bone marrow (BM) histology, survival and disease progression (DP) probability has been observed by several authors in chronic lymphocytic leukemia (CLL). The prognostic value of BM histologic patterns on survival and disease progression probability was investigated in 335 B-CLL patients. RESULTS. Actuarial survival probability estimated by univariate analysis proved to be significantly influenced by stage (p
ISSN:0390-6078
1592-8721