Heterogeneity of Junin virus strains

Argentine Hemorrhagic Fever (AHF), caused by Junin virus (JV), is a severe human disease which is sometimes characterized by predominantly hemorrhagic signs, while other cases are dominated by neurological manifestations. Neither the natural rodent host, Calomys , nor mice develop systemic disease r...

Full description

Saved in:
Bibliographic Details
Published in:Medical microbiology and immunology 1986-01, Vol.175 (2-3), p.169-172
Main Authors: Kenyon, R H, McKee, Jr, K T, Maiztegui, J I, Green, D E, Peters, C J
Format: Article
Language:English
Subjects:
Animals
Antibody-Dependent Cell Cytotoxicity
Arenaviridae - classification
Arenaviruses, New World - classification
Arenaviruses, New World - isolation & purification
Arenaviruses, New World - pathogenicity
Brain - microbiology
Cell Line
Cercopithecus aethiops
Complement System Proteins - immunology
Guinea Pigs
Hemorrhagic Fever, American - immunology
Hemorrhagic Fever, American - microbiology
Hemorrhagic Fever, American - pathology
Junin virus
Kidney
Virus Cultivation
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Argentine Hemorrhagic Fever (AHF), caused by Junin virus (JV), is a severe human disease which is sometimes characterized by predominantly hemorrhagic signs, while other cases are dominated by neurological manifestations. Neither the natural rodent host, Calomys , nor mice develop systemic disease resembling human AHF. Infected guinea pigs and subhuman primates do, however, show the characteristic pathology of human AHF. The authors report some results of in vivo and in vitro testing observed with human JV isolates.
ISSN:0300-8584
1432-1831
DOI:10.1007/BF02122442