Pathogenesis of lentivirus infections

Following infection of animals or humans, lentiviruses play a prolonged game of hide and seek with the host's immune system which results in a slowly developing multi-system disease. Emerging knowledge of the disease processes is of some relevance to acquired immune deficiency syndrome (AIDS),...

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Bibliographic Details
Published in:Nature (London) 1986-07, Vol.322 (6075), p.130-136
Main Author: Haase, Ashley T
Format: Article
Language:English
Subjects:
Acquired Immunodeficiency Syndrome - immunology
Acquired Immunodeficiency Syndrome - transmission
AIDS/HIV
Animals
Antigens, Viral - analysis
Biological and medical sciences
Cachexia - etiology
Cells, Cultured
Epitopes
Gene Expression Regulation
General aspects
Genes, Viral
Goats
Horses
Humanities and Social Sciences
Humans
Immunologic Deficiency Syndromes - etiology
Infectious diseases
lentivirus
Medical sciences
multidisciplinary
Retroviridae Infections - etiology
Retroviridae Infections - immunology
Retroviridae Infections - veterinary
review-article
Science
Science (multidisciplinary)
Sheep
Slow Virus Diseases - etiology
Viral diseases
Viral Vaccines
Virus Replication
Visna-maedi virus - genetics
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Description
Summary:Following infection of animals or humans, lentiviruses play a prolonged game of hide and seek with the host's immune system which results in a slowly developing multi-system disease. Emerging knowledge of the disease processes is of some relevance to acquired immune deficiency syndrome (AIDS), which is caused by a virus possessing many of the characteristics of a lentivirus.
ISSN:0028-0836
1476-4687
DOI:10.1038/322130a0