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Identification of a putative second T-cell receptor
Framework monoclonal antibodies have identified a population of human lymphocytes that express the T3 glycoprotein but not the T-cell receptor (TCR) α- and β-subunits. Chemical crosslinking experiments reveal that these lymphocytes express novel T3-associated polypeptides, one of which appears to be...
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| Published in: | Nature (London) 1986-07, Vol.322 (6075), p.145-149 |
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| Main Authors: | , , , , , , , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c364t-439b17c29678bba5f81d206f87d2668d4f49db2f2aa1053916fbdf21511d07743 |
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| cites | cdi_FETCH-LOGICAL-c364t-439b17c29678bba5f81d206f87d2668d4f49db2f2aa1053916fbdf21511d07743 |
| container_end_page | 149 |
| container_issue | 6075 |
| container_start_page | 145 |
| container_title | Nature (London) |
| container_volume | 322 |
| creator | Dialynas, Deno P Krangel, Michael S Brenner, Michael B Strominger, Jack L Smith, John A Ip, Stephen Rosen, Fred McLean, Joanne Owen, Frances L Seidman, J. G |
| description | Framework monoclonal antibodies have identified a population of human lymphocytes that express the T3 glycoprotein but not the T-cell receptor (TCR) α- and β-subunits. Chemical crosslinking experiments reveal that these lymphocytes express novel T3-associated polypeptides, one of which appears to be the product of the Tγ gene. The other polypeptide may represent a fourth TCR subunit, designated Tδ. |
| doi_str_mv | 10.1038/322145a0 |
| format | article |
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Psychology</subject><subject>Fundamental immunology</subject><subject>Humanities and Social Sciences</subject><subject>Humans</subject><subject>Immunobiology</subject><subject>Immunologic Deficiency Syndromes - immunology</subject><subject>multidisciplinary</subject><subject>Nucleic Acid Hybridization</subject><subject>Organs and cells involved in the immune response</subject><subject>Receptors, Antigen, T-Cell - analysis</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><issn>0028-0836</issn><issn>1476-4687</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><recordid>eNpt0E1LwzAYB_AgypxT8AsoPYjooZr3pEcZvgwGXua5pHmRji6dSSv47c1oNy-eQvj_8jzhD8Algg8IEvlIMEaUKXgEpogKnlMuxTGYQohlDiXhp-AsxjWEkCFBJ2BCBGPpyRSQhbG-q12tVVe3PmtdprJt36Xbt82i1a032SrXtmmyYLXddm04BydONdFejOcMfLw8r-Zv-fL9dTF_WuaacNrllBQVEhoXXMiqUsxJZDDkTgqDOZeGOlqYCjusFIKMFIi7yjiMGEIGCkHJDNwOc7eh_ept7MpNHXc_Ud62fSwFLzBkFCV4N0Ad2hiDdeU21BsVfkoEy10_5b6fRK_GmX21seYAx0JSfjPmKmrVuKC8ruOBSSgRlSyx-4HFlPhPG8p12wef2vhv5fVgver6YP9W7sEv7USBUA</recordid><startdate>19860710</startdate><enddate>19860710</enddate><creator>Dialynas, Deno P</creator><creator>Krangel, Michael S</creator><creator>Brenner, Michael B</creator><creator>Strominger, Jack L</creator><creator>Smith, John A</creator><creator>Ip, Stephen</creator><creator>Rosen, Fred</creator><creator>McLean, Joanne</creator><creator>Owen, Frances L</creator><creator>Seidman, J. 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| identifier | ISSN: 0028-0836 |
| ispartof | Nature (London), 1986-07, Vol.322 (6075), p.145-149 |
| issn | 0028-0836 1476-4687 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_76920541 |
| source | Springer Nature - Connect here FIRST to enable access |
| subjects | Analysis of the immune response. Humoral and cellular immunity Antibodies, Monoclonal Biological and medical sciences Cell Line DNA Electrophoresis Fundamental and applied biological sciences. Psychology Fundamental immunology Humanities and Social Sciences Humans Immunobiology Immunologic Deficiency Syndromes - immunology multidisciplinary Nucleic Acid Hybridization Organs and cells involved in the immune response Receptors, Antigen, T-Cell - analysis Science Science (multidisciplinary) |
| title | Identification of a putative second T-cell receptor |
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