FDG-PET for predicting the prognosis of malignant lymphoma

To evaluate the usefulness of FDG-PET as a predictor of prognosis, 34 patients with untreated malignant lymphoma in the head and neck region were studied. After FDG-PET and treatment, they were observed from 15 to 50 months. Tumors which were aggressive and resistant to treatment tended to show high...

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Bibliographic Details
Published in:Annals of nuclear medicine 1994-09, Vol.8 (3), p.187-191
Main Authors: Okada, J, Oonishi, H, Yoshikawa, K, Itami, J, Uno, K, Imaseki, K, Arimizu, N
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Deoxyglucose - analogs & derivatives
Fluorine Radioisotopes
Fluorodeoxyglucose F18
Glucose - metabolism
Head and Neck Neoplasms - diagnostic imaging
Head and Neck Neoplasms - metabolism
Head and Neck Neoplasms - therapy
Hodgkin Disease - diagnostic imaging
Hodgkin Disease - therapy
Humans
Lymphoma - diagnostic imaging
Lymphoma - metabolism
Lymphoma - therapy
Lymphoma, Non-Hodgkin - diagnostic imaging
Lymphoma, Non-Hodgkin - therapy
Middle Aged
Prognosis
Proportional Hazards Models
Survival Rate
Tomography, Emission-Computed
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Summary:To evaluate the usefulness of FDG-PET as a predictor of prognosis, 34 patients with untreated malignant lymphoma in the head and neck region were studied. After FDG-PET and treatment, they were observed from 15 to 50 months. Tumors which were aggressive and resistant to treatment tended to show high uptake of FDG. The survival rate of patients with high uptake of FDG, DAR > or = 8, was lower than the rate of the other patients. It is considered to be useful to add FDG uptake of the tumor to other prognostic factors for predicting the prognosis.
ISSN:0914-7187
1864-6433
DOI:10.1007/BF03164996