Occult papillary carcinoma of the thyroid in children and young adults: A systemic autopsy study in Finland

The thyroids from 93 autopsies performed on children and young adults younger than age 40 years, were subserially sectioned at 2‐to 3‐mm intervals. Thirteen thyroids revealed 17 foci of occult papillary carcinoma (OPC), giving a prevalence rate of 14%. The youngest affected patient was a boy aged 18...

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Bibliographic Details
Published in:Cancer 1986-08, Vol.58 (3), p.715-719
Main Authors: Franssila, Kaarle O., Rubén Harach, H.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age Factors
Biological and medical sciences
Carcinoma, Papillary - epidemiology
Carcinoma, Papillary - pathology
Child
Child, Preschool
Endocrinopathies
Female
Finland
Humans
Infant
Male
Malignant tumors
Medical sciences
Sex Factors
Thyroid Gland - pathology
Thyroid Neoplasms - epidemiology
Thyroid Neoplasms - pathology
Thyroid. Thyroid axis (diseases)
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Summary:The thyroids from 93 autopsies performed on children and young adults younger than age 40 years, were subserially sectioned at 2‐to 3‐mm intervals. Thirteen thyroids revealed 17 foci of occult papillary carcinoma (OPC), giving a prevalence rate of 14%. The youngest affected patient was a boy aged 18 years. The prevalence rate of individuals between age 18 and 40 years was 27%. The rate appears to be rather constant in adults, although there may be a slight rise in middle age. The prevalence rate was higher for males, but no statistically significant difference was seen. The arise of OPCs after puberty would favor the view that hormonal factors are related to their appearance.Cancer 58:715‐719, 1986.
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(19860801)58:3<715::AID-CNCR2820580319>3.0.CO;2-P