Effect of Antipyretic Drugs in Children with Malaria

A comparison of different antipyretics in children with malaria showed a small effect of naproxen, but not of metamizol, on the reduction of fever peaks. Antipyretic treatment had no effect on fever clearance and therefore should be used cautiously in the treatment of malaria.

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Bibliographic Details
Published in:Clinical infectious diseases 2001-03, Vol.32 (5), p.838-841
Main Authors: Lell, Bertrand, Sovric, Milena, Schmid, Daniela, Luckner, Doris, Herbich, Klaus, Long, Hua Yan, Graninger, Wolfgang, Kremsner, Peter G.
Format: Article
Language:English
Subjects:
Analgesics
Analgesics, Non-Narcotic - therapeutic use
Anti-Inflammatory Agents, Non-Steroidal - therapeutic use
Antimalarials
Antipyretics
Biological and medical sciences
Blood
Brief Reports
Child
Child, Preschool
Children
Cytokines
Dipyrone - therapeutic use
Fever
Fever - drug therapy
Humans
Infections
Malaria
Malaria, Falciparum - parasitology
Malaria, Falciparum - physiopathology
Medical sciences
Metamizol
Naproxen
Naproxen - therapeutic use
Neuropharmacology
Parasitemia
Parasitemia - parasitology
Parasitemia - physiopathology
Parasites
Pharmacology. Drug treatments
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Description
Summary:A comparison of different antipyretics in children with malaria showed a small effect of naproxen, but not of metamizol, on the reduction of fever peaks. Antipyretic treatment had no effect on fever clearance and therefore should be used cautiously in the treatment of malaria.
ISSN:1058-4838
1537-6591
DOI:10.1086/319217