Multicenter Case-Control Study of Risk Factors for Histoplasmosis in Human Immunodeficiency Virus-Infected Persons

We conducted a multicenter case-control study to identify risk factors for histoplasmosis among persons with acquired immunodeficiency syndrome (AIDS) and to evaluate predictors of a poor outcome (defined as death or admission to the intensive care unit). Patients with histoplasmosis were each match...

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Bibliographic Details
Published in:Clinical infectious diseases 2001-04, Vol.32 (8), p.1215-1220
Main Authors: Hajjeh, R. A., Pappas, P. G., Henderson, H., Lancaster, D., Bamberger, D. M., Skahan, K. J., Phelan, M. A., Cloud, G., Holloway, M., Kauffman, C. A., Wheat, L. J.
Format: Article
Language:English
Subjects:
Adult
Aged
AIDS
AIDS-Related Opportunistic Infections - drug therapy
AIDS-Related Opportunistic Infections - physiopathology
AIDS-Related Opportunistic Infections - prevention & control
Animals
Antiretrovirals
Biological and medical sciences
Case-Control Studies
Female
Fungal infections
Health outcomes
Histoplasma
Histoplasmosis
Histoplasmosis - drug therapy
Histoplasmosis - physiopathology
Histoplasmosis - prevention & control
HIV/AIDS
Human immunodeficiency virus
Human viral diseases
Humans
Infections
Infectious diseases
Lymphocytes
Male
Medical sciences
Middle Aged
Predictive Value of Tests
Predisposing factors
Preventive medicine
Risk Factors
Treatment Outcome
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
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Summary:We conducted a multicenter case-control study to identify risk factors for histoplasmosis among persons with acquired immunodeficiency syndrome (AIDS) and to evaluate predictors of a poor outcome (defined as death or admission to the intensive care unit). Patients with histoplasmosis were each matched by age, sex, and CD4 lymphocyte count to 3 controls. From 1996 through 1999, 92 case patients and 252 controls were enrolled. Of the case patients, 81 (89%) were men, 50 (55%) were black, 78 (85%) had a CD4 lymphocyte count of
ISSN:1058-4838
1537-6591
DOI:10.1086/319756