Impaired postprandial gastric myoelectrical activity in Chinese patients with nonulcer dyspepsia

Using a homemade electrogastrography (EGG) system, we studied the characteristics of the myoelectrical rhythm in Chinese patients with nonulcer dyspepsia (NUD). Based on short-term Fourier transformation, recorded slow waves could be automatically analyzed to obtain the following parameters: dominan...

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Bibliographic Details
Published in:Digestive diseases and sciences 2001-02, Vol.46 (2), p.242-249
Main Authors: LU, Ching-Liang, CHEN, Chih-Yen, CHANG, Full-Young, KANG, Lih-Jiun, LEE, Shou-Dong, WU, Han-Chang, KUO, Te-Son
Format: Article
Language:English
Subjects:
Adult
Aged
Biological and medical sciences
Case-Control Studies
China
Dyspepsia - classification
Dyspepsia - diagnosis
Dyspepsia - etiology
Dyspepsia - physiopathology
Electrodiagnosis - instrumentation
Electrodiagnosis - methods
Female
Fourier Analysis
Gastric Emptying - physiology
Gastritis - complications
Gastroenterology. Liver. Pancreas. Abdomen
Helicobacter Infections - complications
Helicobacter pylori
Humans
Male
Medical sciences
Middle Aged
Monitoring, Physiologic - instrumentation
Monitoring, Physiologic - methods
Myoelectric Complex, Migrating - physiology
Other diseases. Semiology
Postprandial Period - physiology
Severity of Illness Index
Signal Processing, Computer-Assisted - instrumentation
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
Tropical medicine
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Summary:Using a homemade electrogastrography (EGG) system, we studied the characteristics of the myoelectrical rhythm in Chinese patients with nonulcer dyspepsia (NUD). Based on short-term Fourier transformation, recorded slow waves could be automatically analyzed to obtain the following parameters: dominant frequency/power, percent of normal frequency (2-4 cpm), power ratio, etc. EGG parameters, Helicobacter pylori status, histological examination of gastric mucosa, and dyspeptic symptoms were recorded in 27 NUD patients. Compared to 32 healthy controls, the Chinese NUD patients had abnormal postprandial EGG parameters including a lower percentage of regular 2-4 cpm slow waves (70.10 +/- 2.97% vs 79.08 +/- 2.95%, P < 0.05), a lower level of increment of dominant power (0.62, +/- 0.91 vs 3.76 +/- 0.58 dB, P < 0.05), lower power ratio (1.42 +/- 0.28 vs 2.79 +/- 0.39, P < 0.05) and a higher instability coefficient (0.36 +/- 0.03 vs 0.26 +/- 0.03, P < 0.05). However, Helicobacter pylori infection and its associated gastritis did not influence any EGG parameters in NUD patients. Six main dyspeptic symptoms and total symptom score had no correlation with any EGG parameters. In conclusion, Chinese NUD patients may have abnormal postprandial stomach myoelectrical activity, but these EGG abnormalities are not a direct result of Helicobacter pylori infection and its related gastritis and do not contribution to the dyspeptic symptoms.
ISSN:0163-2116
1573-2568
DOI:10.1023/A:1005684328217