Eosinophilic Fasciitis Occurring Four Weeks after the Onset of Dialysis in a Renal Failure Patient

Background: Eosinophilic fasciitis is a rare, scleroderma-like disease that usually affects the extremities of young to middle-aged males. The disease may cause flexion contractures and limit joint mobility and is associated with peripheral eosinophilia. The fascia, by definition, is infiltrated wit...

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Bibliographic Details
Published in:Journal of cutaneous medicine and surgery 2001-01, Vol.5 (1), p.33-36
Main Authors: Florell, Scott R., Egan, Conleth A., Gregory, Martin C., Zone, John J., Petersen, Marta J.
Format: Article
Language:English
Subjects:
Aged
Biological and medical sciences
Eosinophilia - complications
Eosinophilia - immunology
Fasciitis - complications
Fasciitis - immunology
Humans
Male
Medical sciences
Renal Dialysis
Renal Insufficiency - complications
Renal Insufficiency - immunology
Renal Insufficiency - therapy
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
Time Factors
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Summary:Background: Eosinophilic fasciitis is a rare, scleroderma-like disease that usually affects the extremities of young to middle-aged males. The disease may cause flexion contractures and limit joint mobility and is associated with peripheral eosinophilia. The fascia, by definition, is infiltrated with mononuclear cells and typically with eosinophils. Eosinophilic fasciitis may be separated from another sclerodermatous disorder, linear scleroderma, by its response to systemic corticosteroids. The etiology is unclear but eosinophilic fasciitis has numerous disease associations. However, it has not previously been associated with renal failure and hemodialysis. Objective: This article reports a case of eosinophilic fasciitis occurring four weeks following the onset of hemodialysis. Methods: The clinical and histologic features confirmed the diagnosis of eosinophilic fasciitis. He was treated with systemic corticosteroids with good response. Conclusion: This is the first reported patient who developed eosinophilic fasciitis in close temporal relationship with the start of hemodialysis. While eosinophilic fasciitis may be coincidental with a common disorder, namely, renal failure, it is interesting to note that hemodialysis patients often have immune-regulation abnormalities and peripheral eosinophilia.
ISSN:1203-4754
1615-7109
DOI:10.1177/120347540100500108