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A new twist on DNA shuffling increases recombination frequency and expands access to sequence space, facilitating the engineering of new protein activities.

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Bibliographic Details
Published in:Nature biotechnology 2001-04, Vol.19 (4), p.314-315
Main Author: Pelletier, Joelle N
Format: Article
Language:English
Subjects:
Agriculture
Bioinformatics
Biomedical and Life Sciences
Biomedical Engineering/Biotechnology
Biomedicine
Biotechnology
Crossing Over, Genetic
directed evolution
DNA - metabolism
DNA shuffling
Genetic Techniques
Life Sciences
news-and-views
Nucleic Acid Hybridization
Polymerase Chain Reaction
Protein Engineering
Recombination, Genetic
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Description
Summary:A new twist on DNA shuffling increases recombination frequency and expands access to sequence space, facilitating the engineering of new protein activities.
ISSN:1087-0156
1546-1696
DOI:10.1038/86681