Mixed duct-acinar-islet cell tumor of the pancreas: report of a case

A 72-year-old Japanese woman presented at our hospital complaining of altered consciousness on arising every morning. The laboratory findings showed hypoglycemia and hyperinsulinemia. Abdominal ultrasonography revealed a tumor in the body of the pancreas. With a diagnosis of insulinoma, a surgical e...

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Bibliographic Details
Published in:Surgery today (Tokyo, Japan) Japan), 2001-01, Vol.31 (2), p.177-179
Main Authors: Tanakaya, K, Teramoto, N, Konaga, E, Takeuchi, H, Yasui, Y, Takeda, A, Yunoki, Y, Murakami, I
Format: Article
Language:English
Subjects:
Adenoma, Islet Cell - pathology
Aged
Carcinoma, Acinar Cell - pathology
Carcinoma, Pancreatic Ductal - pathology
Female
Humans
Immunohistochemistry
Pancreatic Neoplasms - pathology
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Summary:A 72-year-old Japanese woman presented at our hospital complaining of altered consciousness on arising every morning. The laboratory findings showed hypoglycemia and hyperinsulinemia. Abdominal ultrasonography revealed a tumor in the body of the pancreas. With a diagnosis of insulinoma, a surgical excision of the tumor was performed. A light microscopic examination and an immunohistochemical study revealed the tumor to consist of duct, acinar, and islet cell components. Mixed tumors of the pancreas are rare, and their clinical features and pathogenesis remain unclear. A further accumulation of clinical cases as well as a large number of histopathological studies on these rare mixed tumors is needed.
ISSN:0941-1291
1436-2813
DOI:10.1007/s005950170207