Loading…
Determinants of death following burn injury
Background: Burn care has changed considerably. Early surgery, nutritional support, improved resuscitation and novel skin replacement techniques are now well established. The aim of the study was to establish whether changes in management have improved survival following burn injury and to determine...
Saved in:
| Published in: | British journal of surgery 2001-04, Vol.88 (4), p.583-587 |
|---|---|
| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c5265-e50de275ac346da991b7177e0c0d3b70fb9174cfa87080e73157cea4ec8b07fa3 |
|---|---|
| cites | |
| container_end_page | 587 |
| container_issue | 4 |
| container_start_page | 583 |
| container_title | British journal of surgery |
| container_volume | 88 |
| creator | Muller, M. J. Pegg, S. P. Rule, M. R. |
| description | Background:
Burn care has changed considerably. Early surgery, nutritional support, improved resuscitation and novel skin replacement techniques are now well established. The aim of the study was to establish whether changes in management have improved survival following burn injury and to determine the contributory factors leading to non‐survival.
Methods:
This was a retrospective outcome analysis of data collected from a consecutive series of 4094 patients with burns admitted to a tertiary referral, metropolitan teaching hospital between 1972 and 1996.
Results:
The overall mortality rate was 3·6 per cent. This decreased from 5·3 per cent (1972–1980) to 3·4 per cent (1993–1996) (P = 0·076). The risk of death was increased with increasing burn size (relative risk (RR) 95·90 (95 per cent confidence interval 12·60–729·47) if more than 35 per cent of the total body surface area was burned; P < 0·001) increasing age (RR 7·32 (3·08–17·42) if aged more than 48 years; P < 0·001), inhalation injury (RR 3·61 (2·39–5·47); P < 0·001) and female sex (RR 1·82 (1·23–2·69); P = 0·003). Operative intervention (RR 0·11 (0·06–0·21); P < 0·001) and the presence of an upper limb burn (RR 0·53 (0·35–0·79); P = 0·002) decreased the risk.
Conclusion:
Modern burn care has decreased the mortality rate. Increasing burn size, increasing age, inhalation injury and female sex increased, while operative intervention and an upper limb burn decreased, the risk of death. © 2001 British Journal of Surgery Society Ltd |
| doi_str_mv | 10.1046/j.1365-2168.2001.01726.x |
| format | article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_77043970</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>77043970</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5265-e50de275ac346da991b7177e0c0d3b70fb9174cfa87080e73157cea4ec8b07fa3</originalsourceid><addsrcrecordid>eNpFkNtOg0AQhjdGY-vhFQyJiTcGnN0FBhJvtGqr1ppUjZebZVmUyqGykLZvL9har-Zivn8OHyEWBYeC61_MHMp9z2bUDxwGQB2gyHxnuUP628Yu6QMA2pQz3iMHxsxakIPH9kmPUhYGPgv75PxG17rK00IWtbHKxIq1rD-tpMyycpEWH1bUVIWVFrOmWh2RvURmRh9v6iF5u7t9HYzs8fPwfnA1tpXH2uXag1gz9KTirh_LMKQRUkQNCmIeISRRSNFViQwQAtDIqYdKS1erIAJMJD8kZ-u586r8brSpRZ4apbNMFrpsjEAEl4cILXiyAZso17GYV2kuq5X4e68FTjeANEpmSSULlZotF7YHUt5Sl2tqkWZ69T8FRCdbzETnVHRORSdb_MoWS3H98NL-28btdTw1tV5u47L6Ej5y9MT7ZCgm0-DxaToZixH_ARzHgCA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>77043970</pqid></control><display><type>article</type><title>Determinants of death following burn injury</title><source>Oxford Journals Online</source><creator>Muller, M. J. ; Pegg, S. P. ; Rule, M. R.</creator><creatorcontrib>Muller, M. J. ; Pegg, S. P. ; Rule, M. R.</creatorcontrib><description>Background:
Burn care has changed considerably. Early surgery, nutritional support, improved resuscitation and novel skin replacement techniques are now well established. The aim of the study was to establish whether changes in management have improved survival following burn injury and to determine the contributory factors leading to non‐survival.
Methods:
This was a retrospective outcome analysis of data collected from a consecutive series of 4094 patients with burns admitted to a tertiary referral, metropolitan teaching hospital between 1972 and 1996.
Results:
The overall mortality rate was 3·6 per cent. This decreased from 5·3 per cent (1972–1980) to 3·4 per cent (1993–1996) (P = 0·076). The risk of death was increased with increasing burn size (relative risk (RR) 95·90 (95 per cent confidence interval 12·60–729·47) if more than 35 per cent of the total body surface area was burned; P < 0·001) increasing age (RR 7·32 (3·08–17·42) if aged more than 48 years; P < 0·001), inhalation injury (RR 3·61 (2·39–5·47); P < 0·001) and female sex (RR 1·82 (1·23–2·69); P = 0·003). Operative intervention (RR 0·11 (0·06–0·21); P < 0·001) and the presence of an upper limb burn (RR 0·53 (0·35–0·79); P = 0·002) decreased the risk.
Conclusion:
Modern burn care has decreased the mortality rate. Increasing burn size, increasing age, inhalation injury and female sex increased, while operative intervention and an upper limb burn decreased, the risk of death. © 2001 British Journal of Surgery Society Ltd</description><identifier>ISSN: 0007-1323</identifier><identifier>EISSN: 1365-2168</identifier><identifier>DOI: 10.1046/j.1365-2168.2001.01726.x</identifier><identifier>PMID: 11298629</identifier><identifier>CODEN: BJSUAM</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Science Ltd</publisher><subject>Adolescent ; Adult ; Age Distribution ; Aged ; Biological and medical sciences ; Burns ; Burns - mortality ; Burns - pathology ; Burns - therapy ; Burns, Inhalation - mortality ; Cause of Death ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Logistic Models ; Male ; Medical sciences ; Middle Aged ; Multivariate Analysis ; Queensland - epidemiology ; Retrospective Studies ; Risk Factors ; Sex Distribution ; Survival Analysis ; Traumas. Diseases due to physical agents</subject><ispartof>British journal of surgery, 2001-04, Vol.88 (4), p.583-587</ispartof><rights>2001 British Journal of Surgery Society Ltd</rights><rights>2001 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5265-e50de275ac346da991b7177e0c0d3b70fb9174cfa87080e73157cea4ec8b07fa3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>309,310,314,780,784,789,790,23930,23931,25140,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=934613$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11298629$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Muller, M. J.</creatorcontrib><creatorcontrib>Pegg, S. P.</creatorcontrib><creatorcontrib>Rule, M. R.</creatorcontrib><title>Determinants of death following burn injury</title><title>British journal of surgery</title><addtitle>Br J Surg</addtitle><description>Background:
Burn care has changed considerably. Early surgery, nutritional support, improved resuscitation and novel skin replacement techniques are now well established. The aim of the study was to establish whether changes in management have improved survival following burn injury and to determine the contributory factors leading to non‐survival.
Methods:
This was a retrospective outcome analysis of data collected from a consecutive series of 4094 patients with burns admitted to a tertiary referral, metropolitan teaching hospital between 1972 and 1996.
Results:
The overall mortality rate was 3·6 per cent. This decreased from 5·3 per cent (1972–1980) to 3·4 per cent (1993–1996) (P = 0·076). The risk of death was increased with increasing burn size (relative risk (RR) 95·90 (95 per cent confidence interval 12·60–729·47) if more than 35 per cent of the total body surface area was burned; P < 0·001) increasing age (RR 7·32 (3·08–17·42) if aged more than 48 years; P < 0·001), inhalation injury (RR 3·61 (2·39–5·47); P < 0·001) and female sex (RR 1·82 (1·23–2·69); P = 0·003). Operative intervention (RR 0·11 (0·06–0·21); P < 0·001) and the presence of an upper limb burn (RR 0·53 (0·35–0·79); P = 0·002) decreased the risk.
Conclusion:
Modern burn care has decreased the mortality rate. Increasing burn size, increasing age, inhalation injury and female sex increased, while operative intervention and an upper limb burn decreased, the risk of death. © 2001 British Journal of Surgery Society Ltd</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age Distribution</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Burns</subject><subject>Burns - mortality</subject><subject>Burns - pathology</subject><subject>Burns - therapy</subject><subject>Burns, Inhalation - mortality</subject><subject>Cause of Death</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Female</subject><subject>Humans</subject><subject>Infant</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>Queensland - epidemiology</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Sex Distribution</subject><subject>Survival Analysis</subject><subject>Traumas. Diseases due to physical agents</subject><issn>0007-1323</issn><issn>1365-2168</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><recordid>eNpFkNtOg0AQhjdGY-vhFQyJiTcGnN0FBhJvtGqr1ppUjZebZVmUyqGykLZvL9har-Zivn8OHyEWBYeC61_MHMp9z2bUDxwGQB2gyHxnuUP628Yu6QMA2pQz3iMHxsxakIPH9kmPUhYGPgv75PxG17rK00IWtbHKxIq1rD-tpMyycpEWH1bUVIWVFrOmWh2RvURmRh9v6iF5u7t9HYzs8fPwfnA1tpXH2uXag1gz9KTirh_LMKQRUkQNCmIeISRRSNFViQwQAtDIqYdKS1erIAJMJD8kZ-u586r8brSpRZ4apbNMFrpsjEAEl4cILXiyAZso17GYV2kuq5X4e68FTjeANEpmSSULlZotF7YHUt5Sl2tqkWZ69T8FRCdbzETnVHRORSdb_MoWS3H98NL-28btdTw1tV5u47L6Ej5y9MT7ZCgm0-DxaToZixH_ARzHgCA</recordid><startdate>200104</startdate><enddate>200104</enddate><creator>Muller, M. J.</creator><creator>Pegg, S. P.</creator><creator>Rule, M. R.</creator><general>Blackwell Science Ltd</general><general>Wiley</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200104</creationdate><title>Determinants of death following burn injury</title><author>Muller, M. J. ; Pegg, S. P. ; Rule, M. R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5265-e50de275ac346da991b7177e0c0d3b70fb9174cfa87080e73157cea4ec8b07fa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age Distribution</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Burns</topic><topic>Burns - mortality</topic><topic>Burns - pathology</topic><topic>Burns - therapy</topic><topic>Burns, Inhalation - mortality</topic><topic>Cause of Death</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Female</topic><topic>Humans</topic><topic>Infant</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Multivariate Analysis</topic><topic>Queensland - epidemiology</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Sex Distribution</topic><topic>Survival Analysis</topic><topic>Traumas. Diseases due to physical agents</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Muller, M. J.</creatorcontrib><creatorcontrib>Pegg, S. P.</creatorcontrib><creatorcontrib>Rule, M. R.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Muller, M. J.</au><au>Pegg, S. P.</au><au>Rule, M. R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Determinants of death following burn injury</atitle><jtitle>British journal of surgery</jtitle><addtitle>Br J Surg</addtitle><date>2001-04</date><risdate>2001</risdate><volume>88</volume><issue>4</issue><spage>583</spage><epage>587</epage><pages>583-587</pages><issn>0007-1323</issn><eissn>1365-2168</eissn><coden>BJSUAM</coden><abstract>Background:
Burn care has changed considerably. Early surgery, nutritional support, improved resuscitation and novel skin replacement techniques are now well established. The aim of the study was to establish whether changes in management have improved survival following burn injury and to determine the contributory factors leading to non‐survival.
Methods:
This was a retrospective outcome analysis of data collected from a consecutive series of 4094 patients with burns admitted to a tertiary referral, metropolitan teaching hospital between 1972 and 1996.
Results:
The overall mortality rate was 3·6 per cent. This decreased from 5·3 per cent (1972–1980) to 3·4 per cent (1993–1996) (P = 0·076). The risk of death was increased with increasing burn size (relative risk (RR) 95·90 (95 per cent confidence interval 12·60–729·47) if more than 35 per cent of the total body surface area was burned; P < 0·001) increasing age (RR 7·32 (3·08–17·42) if aged more than 48 years; P < 0·001), inhalation injury (RR 3·61 (2·39–5·47); P < 0·001) and female sex (RR 1·82 (1·23–2·69); P = 0·003). Operative intervention (RR 0·11 (0·06–0·21); P < 0·001) and the presence of an upper limb burn (RR 0·53 (0·35–0·79); P = 0·002) decreased the risk.
Conclusion:
Modern burn care has decreased the mortality rate. Increasing burn size, increasing age, inhalation injury and female sex increased, while operative intervention and an upper limb burn decreased, the risk of death. © 2001 British Journal of Surgery Society Ltd</abstract><cop>Oxford, UK</cop><pub>Blackwell Science Ltd</pub><pmid>11298629</pmid><doi>10.1046/j.1365-2168.2001.01726.x</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0007-1323 |
| ispartof | British journal of surgery, 2001-04, Vol.88 (4), p.583-587 |
| issn | 0007-1323 1365-2168 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_77043970 |
| source | Oxford Journals Online |
| subjects | Adolescent Adult Age Distribution Aged Biological and medical sciences Burns Burns - mortality Burns - pathology Burns - therapy Burns, Inhalation - mortality Cause of Death Child Child, Preschool Female Humans Infant Logistic Models Male Medical sciences Middle Aged Multivariate Analysis Queensland - epidemiology Retrospective Studies Risk Factors Sex Distribution Survival Analysis Traumas. Diseases due to physical agents |
| title | Determinants of death following burn injury |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T14%3A42%3A18IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Determinants%20of%20death%20following%20burn%20injury&rft.jtitle=British%20journal%20of%20surgery&rft.au=Muller,%20M.%20J.&rft.date=2001-04&rft.volume=88&rft.issue=4&rft.spage=583&rft.epage=587&rft.pages=583-587&rft.issn=0007-1323&rft.eissn=1365-2168&rft.coden=BJSUAM&rft_id=info:doi/10.1046/j.1365-2168.2001.01726.x&rft_dat=%3Cproquest_pubme%3E77043970%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c5265-e50de275ac346da991b7177e0c0d3b70fb9174cfa87080e73157cea4ec8b07fa3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=77043970&rft_id=info:pmid/11298629&rfr_iscdi=true |