Ontogenesis of corticotropes and lactotropes in situ in the pituitary gland of the hamster: an immunohistochemical study

The development of corticotropes and lactotropes was investigated in the golden Syrian hamster using an anti-porcine ACTH antiserum and a homologous anti-hamster PRL antiserum. Oval corticotropes were first visible in the ventral region of the pars distalis at 13 days of gestation. By the end of ges...

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Bibliographic Details
Published in:Cell and tissue research 1986-09, Vol.245 (3), p.673-679
Main Authors: CAMPBELL, G. T, WAGONER, J, BORER, K. T, KELCH, R. P, CORLEY, K
Format: Article
Language:English
Subjects:
Adrenocorticotropic Hormone - analysis
Animals
Applied sciences
Biological and medical sciences
Cricetinae
Exact sciences and technology
Female
Fetus
Fundamental and applied biological sciences. Psychology
Hormones and neuropeptides. Regulation
Hypothalamus. Hypophysis. Epiphysis. Urophysis
Immune Sera
Immunoenzyme Techniques
Mesocricetus
Other techniques and industries
Pituitary Gland - cytology
Pituitary Gland - embryology
Pregnancy
Prolactin - analysis
Vertebrates: endocrinology
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Summary:The development of corticotropes and lactotropes was investigated in the golden Syrian hamster using an anti-porcine ACTH antiserum and a homologous anti-hamster PRL antiserum. Oval corticotropes were first visible in the ventral region of the pars distalis at 13 days of gestation. By the end of gestation, corticotropes were found throughout the pars distalis and in the pars intermedia. Corticotropes in the pars distalis of postnatal hamsters were either round or irregularly-shaped, often appearing in clusters. Throughout development, corticotropes often appeared to be surrounding other cells. Scarce, very small lactotropes were first observed in the pars distalis of hamsters on the first postnatal day. The number of these cells, which were either round or polyhedral, increased dramatically between 4 and 20 days of postnatal life. These observations indicate that the sequence of appearance of corticotropes and lactotropes in the hamster is similar to that in other species and that lactotropes are confined to the pars distalis of postnatal hamsters.
ISSN:0302-766X
1432-0878
DOI:10.1007/BF00218571