Main nitrogen balance determinants in malnourished patients

Factors influencing nitrogen balance during total parenteral nutrition have been investigated in 38 malnourished patients studied for a cumulative period of 280 days. According to multiple regression analysis, nitrogen intake (0.213 +/- 0.004 g kg-1 day-1, mean +/- SD) proved to be the major determi...

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Bibliographic Details
Published in:Intensive care medicine 1986-01, Vol.12 (4), p.308-311
Main Authors: RADRIZZANI, D, IAPOCHINO, G, SCHERINI, A, FERRERO, P, DOLBI, S. B, SOLCA, M, COLOMBO, A, LEONI, L, DAMIA, G
Format: Article
Language:English
Subjects:
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Emergency and intensive care: metabolism and nutrition disorders. Enteral and parenteral nutrition
Female
Humans
Intensive care medicine
Male
Medical sciences
Nitrogen - metabolism
Nutrition Disorders - metabolism
Nutrition Disorders - therapy
Parenteral Nutrition, Total
Regression Analysis
Retrospective Studies
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Summary:Factors influencing nitrogen balance during total parenteral nutrition have been investigated in 38 malnourished patients studied for a cumulative period of 280 days. According to multiple regression analysis, nitrogen intake (0.213 +/- 0.004 g kg-1 day-1, mean +/- SD) proved to be the major determinant of a positive nitrogen balance (0.018 +/- 0.004 g kg-1 day-1), followed by non-protein energy intake (43.3 +/- 0.5 kcal kg-1 day-1). Total calorie intake to predicted basal energy expenditure and non protein calorie to nitrogen ratios appeared to have little significance on nitrogen balance, when corrected for the two former variables.
ISSN:0342-4642
1432-1238
DOI:10.1007/BF00261742