Single-dose Therapy with Trimethoprim-Sulfametrole for Chancroid in Females

Women with genital ulcer disease who were culture-positive for Haemophilus ducreyi were treated with a single dose of the drug combination trimethoprim-sulfametrole; the dosage was 640 mg of trimethoprim and 3,200 mg of sulfametrole. All 27 women who were treated with this regimen and adequately fol...

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Bibliographic Details
Published in:Sexually transmitted diseases 1986-07, Vol.13 (3), p.166-168
Main Authors: DYLEWSKI, JOSEPH, D'COSTA, LOURDES J., NSANZE, HERBERT, RONALD, ALLAN R.
Format: Article
Language:English
Subjects:
Adult
Antibacterial agents
Antibiotics. Antiinfectious agents. Antiparasitic agents
Biological and medical sciences
Chancroid - drug therapy
Drug Combinations
Female
Genital Diseases, Female - drug therapy
Humans
Medical sciences
Pharmacology. Drug treatments
Sulfanilamides - administration & dosage
Sulfanilamides - therapeutic use
Trimethoprim - administration & dosage
Trimethoprim - therapeutic use
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Summary:Women with genital ulcer disease who were culture-positive for Haemophilus ducreyi were treated with a single dose of the drug combination trimethoprim-sulfametrole; the dosage was 640 mg of trimethoprim and 3,200 mg of sulfametrole. All 27 women who were treated with this regimen and adequately followed were cured. Thus a single dose of trimethoprim-sulfametrole appears to be an effective treatment regimen for women with chancroid in Kenya.
ISSN:0148-5717
1537-4521
DOI:10.1097/00007435-198607000-00011