Retinal photoreceptor neurons and pinealocytes accumulate mRNA for interphotoreceptor retinoid-binding protein (IRBP)

We have utilized cDNA probes and in situ hybridization techniques to define the subcellular localization of interphotoreceptor retinoid-binding protein (IRBP) mRNA in bovine and monkey retinas. Results suggest that the mRNA is mainly localized in rod photoreceptor neurons within the outer nuclear la...

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Bibliographic Details
Published in:FEBS letters 1986-11, Vol.208 (1), p.133-137
Main Authors: van Veen, Theo, Katial, Albine, Shinohara, Toshimichi, Barrett, D.J., Wiggert, B., Chader, Gerald J., Nickerson, John M.
Format: Article
Language:English
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Summary:We have utilized cDNA probes and in situ hybridization techniques to define the subcellular localization of interphotoreceptor retinoid-binding protein (IRBP) mRNA in bovine and monkey retinas. Results suggest that the mRNA is mainly localized in rod photoreceptor neurons within the outer nuclear layer of the retina. IRBP mRNA is also abundant in cells of the pineal gland, strengthening the analogy between rod photoreceptor cells and pinealocytes.
ISSN:0014-5793
1873-3468
DOI:10.1016/0014-5793(86)81547-2