A genome-integrated hepatitis B virus DNA in human neuroblastoma

An integrated hepatitis B virus (HBV) DNA has been identified in a human neuroblastoma, cloned and sequenced. The integrated HBV DNA is not rearranged, although a 480-bp fragment is deleted. The integrated viral DNA covers the C gene fragment, the region of Pre-S and S, and the 3′-truncated X gene....

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Bibliographic Details
Published in:Gene 1995-01, Vol.152 (2), p.277-278
Main Authors: Tagieva, Nailya E., Gizatullin, Rinat Z., Zakharyev, Vladimir M., Kisselev, Lev L.
Format: Article
Language:English
Subjects:
Base Sequence
C gene
Cloning, Molecular
DNA
DNA, Viral - analysis
DNA, Viral - genetics
genomic library
hepatitis B virus
Hepatitis B virus - genetics
Hepatitis B virus - isolation & purification
Humans
man
Molecular Sequence Data
neuroblastoma
Neuroblastoma - virology
Nucleotide sequence
open reading frame
Virus Integration
X gene
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Description
Summary:An integrated hepatitis B virus (HBV) DNA has been identified in a human neuroblastoma, cloned and sequenced. The integrated HBV DNA is not rearranged, although a 480-bp fragment is deleted. The integrated viral DNA covers the C gene fragment, the region of Pre-S and S, and the 3′-truncated X gene.
ISSN:0378-1119
1879-0038
DOI:10.1016/0378-1119(94)00665-F