A human descendant of the chicken cardiac morphogenic protein ES/130

We report a striking amino-acid sequence similarity between a chicken extracellular matrix protein termed ES/130, involved in early cardiac morphogenesis [Rezaee et al., J. Biol. Chem. 268 (1993) 14404–14411], and a novel human protein termed CG-1, isolated from the glycoprotein fraction of peripher...

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Bibliographic Details
Published in:Gene 1995-02, Vol.153 (2), p.293-294
Main Authors: Print, Cristin G., Krissansen, Geoffrey W.
Format: Article
Language:English
Subjects:
Amino Acid Sequence
Animals
Avian Proteins
Blood Proteins - analysis
Blood Proteins - genetics
Cardiac jelly
Chickens
divergent evolution
extracellular matrix protein
Extracellular Matrix Proteins - analysis
Extracellular Matrix Proteins - genetics
Humans
Membrane Proteins
Molecular Sequence Data
peripheral blood cell
Sequence Alignment
Sequence Homology, Amino Acid
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Summary:We report a striking amino-acid sequence similarity between a chicken extracellular matrix protein termed ES/130, involved in early cardiac morphogenesis [Rezaee et al., J. Biol. Chem. 268 (1993) 14404–14411], and a novel human protein termed CG-1, isolated from the glycoprotein fraction of peripheral blood leukocytes [Print et al., Gene 144 (1994) 221–228]. These two proteins may be homologues which have evolved over a period of 270 × 10 6 years.
ISSN:0378-1119
1879-0038
DOI:10.1016/0378-1119(95)00702-8