Healing potential of cream containing extract of Sphaeranthus indicus on dermal wounds in Guinea pigs

A cream containing ethanolic extract of aerial parts of Sphaeranthus indicus, Linn. (Asteraceae) was evaluated for wound healing activity in guinea pigs. The cream was applied in vivo on the paravertebral area of six excised wounded models once a day for 15 days. The cream significantly enhanced the...

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Bibliographic Details
Published in:Journal of ethnopharmacology 2006-09, Vol.107 (2), p.161-163
Main Authors: Sadaf, Farzana, Saleem, Rubeena, Ahmed, Muhammad, Ahmad, Syed Iqbal, Navaid-ul-Zafar
Format: Article
Language:English
Subjects:
Administration, Cutaneous
Animals
Asteraceae
Asteraceae - chemistry
bioassays
Biological and medical sciences
cell growth
chemical constituents of plants
epithelial cells
Epithelialization
General pharmacology
Guinea Pigs
Medical sciences
medicinal plants
medicinal properties
Neomycin
Ointments
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Plant Components, Aerial - chemistry
plant extracts
Plant Extracts - administration & dosage
Plant Extracts - pharmacology
Plant Extracts - therapeutic use
Skin - injuries
Sphaeranthus indicus
Wound contraction
Wound Healing - drug effects
wound treatment
Wounds, Penetrating - drug therapy
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Summary:A cream containing ethanolic extract of aerial parts of Sphaeranthus indicus, Linn. (Asteraceae) was evaluated for wound healing activity in guinea pigs. The cream was applied in vivo on the paravertebral area of six excised wounded models once a day for 15 days. The cream significantly enhanced the rate of wound contraction and the period of epithelialization comparable to neomycin.
ISSN:0378-8741
1872-7573
DOI:10.1016/j.jep.2006.02.022