The role of dermabrasion and chemical peels in the treatment of patients with xeroderma pigmentosum

We describe our experience with two patients with xeroderma pigmentosum who underwent periodic trichloroacetic acid chemical peels. One also received a full-face dermabrasion. The effect of chemical peeling was more transient than dermabrasion but was associated with less morbidity. Both chemical pe...

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Bibliographic Details
Published in:Journal of the American Academy of Dermatology 1995-04, Vol.32 (4), p.623-626
Main Authors: Nelson, Bruce R., Fader, Darrell J., Gillard, Montgomery, Baker, Shan R., Johnson, Timothy M.
Format: Article
Language:English
Subjects:
Adolescent
Biological and medical sciences
Carcinoma, Basal Cell - prevention & control
Carcinoma, Squamous Cell - prevention & control
Chemexfoliation - adverse effects
Child
Dermabrasion - adverse effects
Dermatology
Facial Neoplasms - prevention & control
Facial Neoplasms - surgery
Female
Follow-Up Studies
Hereditary diseases of the skin. Congenital diseases of the skin. Haemangioma of the skin, of mucosae and of soft tissue
Humans
Medical sciences
Neoplasm Recurrence, Local - prevention & control
Skin Neoplasms - prevention & control
Skin Neoplasms - surgery
Trichloroacetic Acid - therapeutic use
Xeroderma Pigmentosum - surgery
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Summary:We describe our experience with two patients with xeroderma pigmentosum who underwent periodic trichloroacetic acid chemical peels. One also received a full-face dermabrasion. The effect of chemical peeling was more transient than dermabrasion but was associated with less morbidity. Both chemical peeling and dermabrasion provided a prophylactic effect against the development of skin malignancies; the latter had a more pronounced effect.
ISSN:0190-9622
1097-6787
DOI:10.1016/0190-9622(95)90348-8