Acute Myelomonocytic Leukemia with Abnormal Eosinophils Presenting as an Ovarian Mass: A Report of Two Cases and a Review of the Literature

Acute myelomonocytic leukemia is a neoplastic blood disease that can occur as an extramedullary tumor called a granulocytic sarcoma. Granulocytic sarcoma can be the presenting feature of acute leukemia and can occur as an abdominal or pelvic mass. Two cases of granulocytic sarcomas presenting as ova...

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Bibliographic Details
Published in:Gynecologic oncology 1995-02, Vol.56 (2), p.307-311
Main Authors: Drinkard, Lee C., Waggoner, Steven, Stein, Robert N., Byrne, Rebecca A., Larson, Richard A.
Format: Article
Language:English
Subjects:
Adolescent
Biological and medical sciences
Chromosome Aberrations
Chromosomes, Human, Pair 16
Eosinophils - pathology
Female
Hematologic and hematopoietic diseases
Humans
Leukemia, Myeloid - diagnosis
Leukemia, Myeloid - pathology
Leukemia, Myeloid - surgery
Leukemia, Myelomonocytic, Acute - diagnosis
Leukemia, Myelomonocytic, Acute - genetics
Leukemia, Myelomonocytic, Acute - pathology
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Medical sciences
Middle Aged
Ovarian Neoplasms - diagnosis
Ovarian Neoplasms - pathology
Ovarian Neoplasms - surgery
Prognosis
Tomography, X-Ray Computed
Citations: Items that cite this one
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Description
Summary:Acute myelomonocytic leukemia is a neoplastic blood disease that can occur as an extramedullary tumor called a granulocytic sarcoma. Granulocytic sarcoma can be the presenting feature of acute leukemia and can occur as an abdominal or pelvic mass. Two cases of granulocytic sarcomas presenting as ovarian masses in patients with acute myelomonocytic leukemia with a characteristic inversion of chromosome 16 are described and the current literature regarding treatment and prognosis is reviewed.
ISSN:0090-8258
1095-6859
DOI:10.1006/gyno.1995.1052