Effect of Muscular Activity on the Turnover Rate of Actin and Myosin Heavy and Light Chains in Different Types of Skeletal Muscle. I. Changes in the Turnover Rate of Myosin and Actin During and After Single-Bout Physical Activity

Abstract During a single-bout of 6-h swimming, myosin heavy chain (HC) and actin in m. gastrocnemius turned over more slowly than they did in the pre-exercise period, whereas the turnover rate of myosin light chain (LC) increased; 48 h after swimming, actin and myosin HC had a significantly higher t...

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Bibliographic Details
Published in:International journal of sports medicine 1986-10, Vol.7 (5), p.287-290
Main Authors: Seene, T., Alev, K., Pehme, A.
Format: Article
Language:English
Subjects:
Actins - biosynthesis
Actins - metabolism
Animals
Biological and medical sciences
Endopeptidases - metabolism
Fundamental and applied biological sciences. Psychology
Hydrogen-Ion Concentration
Leucine - metabolism
Male
Muscles - metabolism
Myosins - biosynthesis
Myosins - metabolism
Physical Exertion
Rats
Rats, Inbred Strains
Space life sciences
Striated muscle. Tendons
Swimming
Vertebrates: osteoarticular system, musculoskeletal system
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Summary:Abstract During a single-bout of 6-h swimming, myosin heavy chain (HC) and actin in m. gastrocnemius turned over more slowly than they did in the pre-exercise period, whereas the turnover rate of myosin light chain (LC) increased; 48 h after swimming, actin and myosin HC had a significantly higher turnover rate, but the turnover rate of myosin LC remained at the pre-exercise level. Exercise caused a remarkable decrease in the incorporation of the 14 C leucine into actin and myosin HC, but an increase in the incorporation into myosin LC. An elevation of the synthesis rate of actin and myosin HC was observed 48 h after exercise. Myofibrillar proteinase activity at alkaline pH reached its maximum level during exercise, but the same was observed for the proteolytic activity at acid pH 6 h and at neutral pH 24 h after exercise.
ISSN:0172-4622
1439-3964
DOI:10.1055/s-2008-1025776