CHANGES IN BRAIN SURFACE OXYGEN TENSION DURING PROFOUND HYPOTENSION INDUCED WITH SODIUM NITROPRUSSIDE OR ADENOSINE IN THE SHEEP

Brain suface oxygen tensions were measured, in sheep (n = 8), with a seven-barrelled mini-electrode polarized by sweep potentials. Mean arterial pressure was reduced to 30 mm Hg with either sodium nitroprusside or adenosine. At this value of mean arterial pressure, oxygen supply to cerebral tissue w...

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Bibliographic Details
Published in:British journal of anaesthesia : BJA 1986-12, Vol.58 (12), p.1422-1426
Main Authors: LAYCOCK, J.R.D., COAKHAM, H.B., SILVER, I.A., WALTERS, F.J.M.
Format: Article
Language:English
Subjects:
Adenosine
Animals
Brain - physiology
Ferricyanides
Hypotension, Controlled
Nitroprusside
Oxygen - physiology
Partial Pressure
Sheep
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Summary:Brain suface oxygen tensions were measured, in sheep (n = 8), with a seven-barrelled mini-electrode polarized by sweep potentials. Mean arterial pressure was reduced to 30 mm Hg with either sodium nitroprusside or adenosine. At this value of mean arterial pressure, oxygen supply to cerebral tissue was impaired. There was no significant difference between the two agents in the degree to which the oxygen supply was reduced.
ISSN:0007-0912
1471-6771
DOI:10.1093/bja/58.12.1422