Human chromosome 10 loci map to three different sheep chromosomes

The interleukin 2 receptor (IL2RA), a human Chromosome (Chr) 10p locus, was mapped to sheep Chr 13q12-q15 by in situ hybridization. Two loci from human Chr 10q, cytochrome P450 subfamily XVII (CYP17) and the tachykinin 2 receptor (TAC2R), were assigned to sheep Chrs 22q21-q23 and 25q14-q23 respectiv...

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Bibliographic Details
Published in:Mammalian genome 1995-01, Vol.6 (1), p.46-48
Main Authors: Ansari, H A, Pearce, P D, Maher, D W, Broad, T E
Format: Article
Language:English
Subjects:
Animals
Cattle - genetics
Chromosome Mapping - veterinary
Chromosomes, Human, Pair 10
Genetic Markers
Humans
In Situ Hybridization
Sheep - genetics
Species Specificity
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Summary:The interleukin 2 receptor (IL2RA), a human Chromosome (Chr) 10p locus, was mapped to sheep Chr 13q12-q15 by in situ hybridization. Two loci from human Chr 10q, cytochrome P450 subfamily XVII (CYP17) and the tachykinin 2 receptor (TAC2R), were assigned to sheep Chrs 22q21-q23 and 25q14-q23 respectively. The assignment of IL2RA allows the provisional assignment of the previously unassigned sheep syntenic group U15 to sheep Chr 13. Sheep linkage group 5 is predicted to be located on sheep Chr 25 on the basis of the TAC2R assignment.
ISSN:0938-8990
1432-1777
DOI:10.1007/BF00350893