Lymphedema-induced lymphangiosarcoma

A series of eight patients with chronic lymphedema-related lymphangiosarcoma is presented. All but one case showed a typical rapid progression and fatal outcome, as has been reported in other series. In one patient the lymphangiosarcoma developed on the chest wall, the axilla and the arm where persi...

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Bibliographic Details
Published in:European journal of surgical oncology 1995-04, Vol.21 (2), p.155-158
Main Authors: Janse, Arieke J., Coevorden, Frits van, Peterse, Hans, Keus, Ronald B., Dongen, Johannes A. van
Format: Article
Language:English
Subjects:
Aged
angiosarcoma
Biological and medical sciences
breast carcinoma
Breast Neoplasms - complications
Breast Neoplasms - therapy
Combined Modality Therapy - adverse effects
Dermatology
Female
Humans
lymphangiosarcoma
Lymphangiosarcoma - diagnosis
Lymphangiosarcoma - etiology
Lymphangiosarcoma - therapy
lymphedema
Lymphedema - complications
Lymphedema - congenital
Lymphedema - etiology
Male
Medical sciences
Middle Aged
Stewart-Treves syndrome
Tumors of the skin and soft tissue. Premalignant lesions
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Summary:A series of eight patients with chronic lymphedema-related lymphangiosarcoma is presented. All but one case showed a typical rapid progression and fatal outcome, as has been reported in other series. In one patient the lymphangiosarcoma developed on the chest wall, the axilla and the arm where persisting lymphedema and fibrosis occurred after bilateral mastectomy and bilateral postoperative radiotherapy. In this patient an asymptomatic course and slow locoregional progression of lesions was seen. The clinical picture, the etiological considerations and the therapeutic options of the lymphedema-induced lymphangiosarcoma with regard to the literature are discussed.
ISSN:0748-7983
1532-2157
DOI:10.1016/S0748-7983(95)90270-8