Codon usage, genetic code and phylogeny of Dictyostelium discoideum mitochondrial DNA as deduced from a 7.3-kb region

A region (7376-bp) of the mitochondrial (mt) DNA (54 kb) of the cellular slime mold, Dictyostelium discoideum was sequenced. From the DNA and amino-acid sequence comparisons with known sequences, genes for ATPase subunit 9 (ATP9), cytochrome b (CYTB), NADH dehydrogenase subunits 1, 3 and 6 (ND1, ND3...

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Bibliographic Details
Published in:Current genetics 1995-02, Vol.27 (3), p.249-256
Main Authors: Angata, K, Kuroe, K, Yanagisawa, K, Tanaka, Y. (Tsukuba Univ., Ibaraki (Japan). Inst. of Biological Sciences)
Format: Article
Language:English
Subjects:
ADN
Amino Acid Sequence
Animals
Base Sequence
Biological Evolution
CODE GENETIQUE
CODIGO GENETICO
Codon
Codon capture theory
Dictyostelium - classification
Dictyostelium - genetics
DICTYOSTELIUM DISCOIDEUM
DNA, Mitochondrial - chemistry
FILOGENIA
Genes, Plant
Genes, Protozoan
Genetic Code
GENETICA MOLECULAR
GENETIQUE MOLECULAIRE
Mitochondrial DNA
MITOCHONDRIE
MITOCONDRIA
Molecular phylogeny
Molecular Sequence Data
Pflanzenzuechtung
PHYLOGENIE
Phylogeny
Restriction Mapping
RNA, Transfer - genetics
Sequence Homology, Nucleic Acid
Space life sciences
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Summary:A region (7376-bp) of the mitochondrial (mt) DNA (54 kb) of the cellular slime mold, Dictyostelium discoideum was sequenced. From the DNA and amino-acid sequence comparisons with known sequences, genes for ATPase subunit 9 (ATP9), cytochrome b (CYTB), NADH dehydrogenase subunits 1, 3 and 6 (ND1, ND3 and ND6), small subunit rRNA (SSU rRNA) and seven tRNAs (Arg Asn, Cys, Lys, f-Met, Met and Pro) have been identified. The sequenced region of the mtDNA has a high average A+T-content (70.8%). The A+T-content of proteingenes (73.6%) is considerably higher than that of RNA genes (61.3%). Even with the strong AT-bias, the genetic code employed is most probably the universal one. All seven tRNAs are able to form typical clover leaf structures. The molecular phylogenetic trees of CYTB and SSU rRNA suggest that D. discoideum is closer to green plants than to animals and fungi.
ISSN:0172-8083
1432-0983
DOI:10.1007/BF00326157