Erythrocyte survival following intraoperative autotransfusion in spinal surgery: an in vivo comparative study and 5-year update

A 5-year prospective study of intraoperative blood transfusion in 239 patients, most of whom had major spinal surgery, has been completed. Autotransfusion is safe, practical, and it reduces donor blood requirements and total blood loss by 50%. It eliminates host versus graft reactions and disease tr...

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Bibliographic Details
Published in:Spine (Philadelphia, PA. 1976) PA. 1976), 1986-11, Vol.11 (9), p.879-882
Main Authors: RAY, J. M, FLYNN, J. C, BIERMAN, A. H
Format: Article
Language:English
Subjects:
Adolescent
Adult
Anesthesia
Anesthesia depending on type of surgery
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Blood Transfusion, Autologous - methods
Child
Chromium Radioisotopes
Erythrocyte Aging
Humans
Medical sciences
Middle Aged
Orthopedic surgery. Maxillofacial surgery. Otorhinolaryngologic surgery. Stomatology. Ophtalmology. Investigation and treatment technics
Prospective Studies
Spine - surgery
Time Factors
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Summary:A 5-year prospective study of intraoperative blood transfusion in 239 patients, most of whom had major spinal surgery, has been completed. Autotransfusion is safe, practical, and it reduces donor blood requirements and total blood loss by 50%. It eliminates host versus graft reactions and disease transmission. In 33 patients having major spinal surgery, the in vivo survival of autologous, homologous, and processed red blood cells (RBC) using the Cell Saver System were compared. The RBC survival studies were performed using chromium51 isotope labeling technique. The long-term survival of processed RBCs was normal over a 30-day period. There was no significant difference in the survival rate of the three groups studied.
ISSN:0362-2436
1528-1159
DOI:10.1097/00007632-198611000-00006