Systemic autonomic neuropathy in open-angle glaucoma

Systemic autonomic nerve function was assessed in 67 patients with open-angle glaucoma and 76 age- and sex-matched control subjects, using a series of well-established tests based upon cardiovascular reflex responses to standardised stimuli. Parasympathetic neuropathy was present in 37.3% of open-an...

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Bibliographic Details
Published in:Documenta ophthalmologica 1986, Vol.64 (2), p.179-185
Main Authors: CLARK, C. V, MAPSTONE, R
Format: Article
Language:English
Subjects:
Aged
Autonomic Nervous System - physiopathology
Autonomic Nervous System Diseases - classification
Autonomic Nervous System Diseases - etiology
Biological and medical sciences
Glaucoma and intraocular pressure
Glaucoma, Open-Angle - complications
Glaucoma, Open-Angle - physiopathology
Humans
Medical sciences
Middle Aged
Ophthalmology
Parasympathetic Nervous System - physiopathology
Sympathetic Nervous System - physiopathology
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Summary:Systemic autonomic nerve function was assessed in 67 patients with open-angle glaucoma and 76 age- and sex-matched control subjects, using a series of well-established tests based upon cardiovascular reflex responses to standardised stimuli. Parasympathetic neuropathy was present in 37.3% of open-angle glaucoma patients compared with 2.6% of the control group. Demonstration of a significant association between autonomic neuropathy and primary glaucoma may provide a logical rationale for the efficacy of autonomic medication in glaucoma therapeutics; the prognostic implications are discussed.
ISSN:0012-4486
1573-2622