Recommendations for Treatment of Chancroid, 1993

Since the 1989 Sexually Transmitted Diseases Treatment Guidelines were published by the Centers for Disease Control and Prevention, changes in the efficacy of the recommended and alternative regimens for the treatment of Haemophilus ducreyi infections have been described. Among recommended agents, e...

Full description

Saved in:
Bibliographic Details
Published in:Clinical infectious diseases 1995-04, Vol.20 (Supplement-1), p.S39-S46
Main Authors: Schulte, Joann M., Schmid, George P.
Format: Article
Language:English
Subjects:
AIDS
AIDS/HIV
Anti-Bacterial Agents - therapeutic use
Antibacterial agents
Antibiotics
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antimicrobials
Biological and medical sciences
Chancroid
Chancroid - drug therapy
Dosage
Haemophilus ducreyi
HIV
Humans
Infections
Medical sciences
Pharmacology. Drug treatments
Sexually transmitted diseases
Ulcers
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Since the 1989 Sexually Transmitted Diseases Treatment Guidelines were published by the Centers for Disease Control and Prevention, changes in the efficacy of the recommended and alternative regimens for the treatment of Haemophilus ducreyi infections have been described. Among recommended agents, erythromycin remains effective, and although a single dose of ceftriaxone appears to remain effective in the United States, limited data from Kenya have shown that this regimen has been associated with treatment failures. Of alternative treatment regimens, trimethoprim-sulfamethoxazole has been associated with widespread failure, but little work has been done to further evaluate the efficacy of the amoxicillin/clavulanic acid and ciprofloxacin regimens. Of the new antimicrobials, azithromycin has been very effective in the United States, but the efficacy of this drug elsewhere has not been thoroughly evaluated. Fleroxacin has been very effective in Kenya. Data from Africa indicate that patients who are infected with the human immunodeficiency virus do not respond to therapy as well as patients who are not, and patients who are uncircumcised may not respond as well to therapy as do patients who are circumcised.
ISSN:1058-4838
1537-6591
DOI:10.1093/clinids/20.Supplement_1.S39