The uptake of enflurane during anaesthesia

Summary The uptake of enflurane at a constant end‐expired concentration of 2% in oxygen was studied in 38 patients, ASA 1 or 2, undergoing elective orthopaedic procedures. The anaesthetic was administered using a computer‐controlled closed circle system. Following an initial 4 min period during whic...

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Bibliographic Details
Published in:Anaesthesia 1995-06, Vol.50 (6), p.491-495
Main Authors: DEVCHAND, D., CHAKRABARTI, M. K., LOCKWOOD, G. G.
Format: Article
Language:English
Subjects:
Adult
Aged
Anaesthetics, volatile
Anesthesia, Inhalation
Anesthetics. Neuromuscular blocking agents
Biological and medical sciences
computer‐controlled anaesthesia
enflurane
Enflurane - pharmacokinetics
Humans
Medical sciences
Microcomputers
Middle Aged
Models, Chemical
Neuropharmacology
Pharmacokinetics
Pharmacology. Drug treatments
Spine - surgery
Time Factors
uptake
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Description
Summary:Summary The uptake of enflurane at a constant end‐expired concentration of 2% in oxygen was studied in 38 patients, ASA 1 or 2, undergoing elective orthopaedic procedures. The anaesthetic was administered using a computer‐controlled closed circle system. Following an initial 4 min period during which the expired concentration of enflurane was established, the rate of uptake of enflurane showed a triexponential decline. The mean cumulative use of enflurane after 60min was 10.7ml, and after 120min was 18.4ml.
ISSN:0003-2409
1365-2044
DOI:10.1111/j.1365-2044.1995.tb06036.x