Estimation of arterial PCO2 during high frequency jet ventilation: studies in the dog

The arterial to end-tidal PCO2 difference (PaCO2-PE'CO2) was measured in five anaesthetized dogs during controlled ventilation at 0.25 Hz (15 b.p.m.) and during high frequency jet ventilation at 1, 3 and 5 Hz. Because of the slow response of the infra-red carbon dioxide analyser, satisfactory r...

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Bibliographic Details
Published in:British journal of anaesthesia : BJA 1987-02, Vol.59 (2), p.240-246
Main Authors: MORTIMER, A. J, CANNON, D. P, SYKES, M. K
Format: Article
Language:English
Subjects:
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Animals
Arteries
Biological and medical sciences
Carbon Dioxide - blood
Carbon Dioxide - physiology
Dogs
Emergency and intensive respiratory care
Intensive care medicine
Medical sciences
Respiration, Artificial
Tidal Volume
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Summary:The arterial to end-tidal PCO2 difference (PaCO2-PE'CO2) was measured in five anaesthetized dogs during controlled ventilation at 0.25 Hz (15 b.p.m.) and during high frequency jet ventilation at 1, 3 and 5 Hz. Because of the slow response of the infra-red carbon dioxide analyser, satisfactory recordings of end-tidal carbon dioxide could not be obtained at frequencies greater than 1 Hz. The interruption of high frequency jet ventilation by conventional ventilation resulted in approximately equal arterial and end-tidal PCO2 values during the first breath, and restoration of the normal arterial to end-tidal PCO2 difference by the third breath. It is concluded that, when high frequency jet ventilation at 1, 3 or 5 Hz is interrupted with normal tidal volumes at low frequencies, the arterial PCO2 can be estimated from recordings of the end-tidal PCO2.
ISSN:0007-0912
1471-6771
DOI:10.1093/bja/59.2.240