Hairy cell leukemia—An unusual presentation

Hairy cell leukemia is a chronic lymphoproliferative disorder affecting middle-aged adults, with the median age of 50–55 years. The majority of the patients present with cytopenia. A high count is usually a feature of the hairy cell leukemia variant. We report a case of a 23-year-old male who presen...

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Bibliographic Details
Published in:Leukemia research 1995-07, Vol.19 (7), p.485-487
Main Authors: Goyal, R., Bajpai, S., Chopra, H.K., Shinde, S.C., Badrinath, Y., Sapre, R.S., Nair, C.N., Advani, S.H.
Format: Article
Language:English
Subjects:
Adult
Age of Onset
Biological and medical sciences
Diagnosis, Differential
hairy cell
Hematologic and hematopoietic diseases
Humans
Leukemia
Leukemia, Hairy Cell - diagnosis
Leukemia, Hairy Cell - physiopathology
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Male
Medical sciences
Microscopy, Electron
unusual presentation
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Description
Summary:Hairy cell leukemia is a chronic lymphoproliferative disorder affecting middle-aged adults, with the median age of 50–55 years. The majority of the patients present with cytopenia. A high count is usually a feature of the hairy cell leukemia variant. We report a case of a 23-year-old male who presented with fever and cough of 15 days duration. His peripheral blood count was 63 × 10 9/l. His peripheral blood and bone marrow smear showed hairy cells which were positive for tartarate-resistant acid phosphatase stain. Surface markers and electron microscopic study on peripheral blood ruled out hairy cell leukemia variant as a differential diagnosis.
ISSN:0145-2126
1873-5835
DOI:10.1016/0145-2126(95)00014-F