Contingent Negative Variation During Migraine Attack and Interval: Evidence for Normalization of Slow Cortical Potentials During the Attack

The contingent negative variation (CNV) amplitudes of 16 subjects with migraine without aura were studied during pain-free intervals and during attacks and the results were compared with those of 22 healthy subjects. In 32 trials the CNV amplitudes were calculated for (a) “total interval”, (b) “earl...

Full description

Saved in:
Bibliographic Details
Published in:Cephalalgia 1995-04, Vol.15 (2), p.123-128
Main Authors: Kropp, P, Gerber, W-D
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Contingent negative variation
Contingent Negative Variation - physiology
Evoked Potentials - physiology
Female
habituation
Habituation, Psychophysiologic
Humans
Male
Medical sciences
Middle Aged
migraine
Migraine Disorders - physiopathology
Neurology
Reference Values
Vascular diseases and vascular malformations of the nervous system
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The contingent negative variation (CNV) amplitudes of 16 subjects with migraine without aura were studied during pain-free intervals and during attacks and the results were compared with those of 22 healthy subjects. In 32 trials the CNV amplitudes were calculated for (a) “total interval”, (b) “early CNV component”, (c) “late CNV component”, and (d) habituation. There was a significantly higher total CNV amplitude in migraine subjects during pain-free intervals compared to that of the healthy subjects and migraine patients during an attack. Healthy subjects as well as subjects studied during the attack showed a significant habituation whereas migraine subjects studied during pain-free intervals did not. This suggests that the higher CNV amplitude in migraine patients studied between pain-free attacks may be due in part to impaired habituation.
ISSN:0333-1024
1468-2982
DOI:10.1046/j.1468-2982.1995.015002123.x