Long‐term survival in peritoneal mesothelioma the role of radiotherapy and combined modality treatment

Ten patients with peritoneal mesothelioma were treated at the Joint Center for Radiation Therapy between 1968 and 1985. Six of the ten patients remained free of disease at 19+ to 78+ months after diagnosis. The six patients received sequential surgical debulking, combination chemotherapy, and whole‐...

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Bibliographic Details
Published in:Cancer 1987-06, Vol.59 (11), p.1882-1886
Main Authors: Lederman, Gilbert S., Recht, Abram, Herman, Terence, Osteen, Robert, Corson, Joseph, Antman, Karen H.
Format: Article
Language:English
Subjects:
Abdomen
Adult
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Biological and medical sciences
Combined Modality Therapy
Female
Follow-Up Studies
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Male
Medical sciences
Mesothelioma - radiotherapy
Mesothelioma - surgery
Middle Aged
Peritoneal Neoplasms - radiotherapy
Peritoneal Neoplasms - surgery
Prognosis
Tumors
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Summary:Ten patients with peritoneal mesothelioma were treated at the Joint Center for Radiation Therapy between 1968 and 1985. Six of the ten patients remained free of disease at 19+ to 78+ months after diagnosis. The six patients received sequential surgical debulking, combination chemotherapy, and whole‐abdomen irradiation. Four patients not treated with this multimodality approach died with disease. This approach may have an impact on the natural course of peritoneal mesothelioma, and warrants further study.
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(19870601)59:11<1882::AID-CNCR2820591107>3.0.CO;2-0