Measles and rubella antibody response after measles-mumps-rubella vaccination in children with afebrile upper respiratory tract infection

The effect of concurrent afebrile viral upper respiratory tract infection (URI) on measles and rubella serum antibody response after measles-mumps-rubella (MMR) vaccination was determined in 580 1-year-old children, 369 with URI and 211 without URI, with the use of preimmunization and postimmunizati...

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Bibliographic Details
Published in:The Journal of pediatrics 1995-09, Vol.127 (3), p.432-434
Main Authors: Ratnam, Samuel, West, Roy, Gadag, Veeresh
Format: Article
Language:English
Subjects:
Antibodies, Viral - blood
Biological and medical sciences
Epidemiology. Vaccinations
General aspects
Humans
Infant
Infectious diseases
Measles Vaccine - immunology
Measles virus - immunology
Medical sciences
Mumps Vaccine - immunology
Newfoundland and Labrador
Prospective Studies
Respiratory Tract Infections - immunology
Rubella Vaccine - immunology
Rubella virus - immunology
Time Factors
Vaccines, Combined - immunology
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Summary:The effect of concurrent afebrile viral upper respiratory tract infection (URI) on measles and rubella serum antibody response after measles-mumps-rubella (MMR) vaccination was determined in 580 1-year-old children, 369 with URI and 211 without URI, with the use of preimmunization and postimmunization sera. The presence of URI during the preceding 28 days, at the time of, or up to 7 days after immunization had no effect on the antibody response to either the measles or the rubella component of the vaccine. These findings support the recommendation that MMR vaccine be given to children at the recommended age regardless of the presence of afebrile viral URI. (J P EDIATR 1995;127:432-4)
ISSN:0022-3476
1097-6833
DOI:10.1016/S0022-3476(95)70077-3