Acute leukemia occurring 19 years after treatment of acute lymphoblastic leukemia

A 22‐year‐old woman presented with acute lymphoblastic leukemia (ALL) during pregnancy. She had been successfully treated for ALL at the age of 3 years and had received maintenance treatment for 11 years. Complete remission of 3 years or more is an important factor for long‐term survival and potenti...

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Bibliographic Details
Published in:Cancer 1987-06, Vol.59 (11), p.1963-1965
Main Authors: Reynoso, Eduardo E., Keating, Armand, Baker, Michael A.
Format: Article
Language:English
Subjects:
Acute Disease
Adult
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Biological and medical sciences
Bone Marrow - pathology
Child, Preschool
Female
Hematologic and hematopoietic diseases
Humans
Leukemia - drug therapy
Leukemia - pathology
Leukemia, Lymphoid - drug therapy
Leukemia, Lymphoid - pathology
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Medical sciences
Neoplasms, Multiple Primary
Pregnancy
Remission Induction
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Description
Summary:A 22‐year‐old woman presented with acute lymphoblastic leukemia (ALL) during pregnancy. She had been successfully treated for ALL at the age of 3 years and had received maintenance treatment for 11 years. Complete remission of 3 years or more is an important factor for long‐term survival and potential cure. Relapses may occur in the first 5 years after maintenance is discontinued. Later relapses are distinctly unusual. We have found six more cases of ALL occurring long after the initial remission in the English literature. It is unclear whether late relapse represents true relapse or a second leukemia. Life‐long followup of children with ALL may be necessary.
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(19870601)59:11<1963::AID-CNCR2820591121>3.0.CO;2-C