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Statistically adjusted estimates of geographic mortality profiles

The spatial variation of site-specific cancer mortality rates at the county or state economic area level can provide a) insights into possible etiologic factors and b) the basis for more detailed epidemiologic studies. One difficulty with such studies, especially for rare cancer types, is that unsta...

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Bibliographic Details
Published in:JNCI : Journal of the National Cancer Institute 1987-05, Vol.78 (5), p.805-815
Main Authors: MANTON, K. G, STALLARD, E, WOODBURY, M. A, RIGGAN, W. B, CREASON, J. P, MASON, T. J
Format: Article
Language:English
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Summary:The spatial variation of site-specific cancer mortality rates at the county or state economic area level can provide a) insights into possible etiologic factors and b) the basis for more detailed epidemiologic studies. One difficulty with such studies, especially for rare cancer types, is that unstable local area rate estimates, resulting from small population sizes, can obscure the underlying spatial pattern of disease risk. This paper presents a methodology for producing more stable rate estimates by statistically weighting the local area rate estimate toward the experience at the national level. The methodology is illustrated by the analysis of the spatial variation of two cancer types, bladder and lung, for U.S. white males over the three decades 1950-79.
ISSN:0027-8874
1460-2105