Changes in mean trabecular orientation in the medial condyle of the proximal tibia in osteoarthritis

In osteoarthritis of the knee, degenerative changes occur in the articular cartilage and underlying subchondral bone, particularly of the medial tibial condyle. Cancellous bone sclerosis that accompanies osteoarthritis is not only the result of an increase in bone volume fraction but also a change i...

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Bibliographic Details
Published in:Calcified tissue international 1995-07, Vol.57 (1), p.69-73
Main Authors: Kamibayashi, L, Wyss, U P, Cooke, T D, Zee, B
Format: Article
Language:English
Subjects:
Aged
Humans
Image Processing, Computer-Assisted
Knee Joint - pathology
Middle Aged
Osteoarthritis - pathology
Sclerosis
Tibia - pathology
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Summary:In osteoarthritis of the knee, degenerative changes occur in the articular cartilage and underlying subchondral bone, particularly of the medial tibial condyle. Cancellous bone sclerosis that accompanies osteoarthritis is not only the result of an increase in bone volume fraction but also a change in trabecular structure. In a comparison with age-matched controls (n = 4), osteoarthritis (n = 11) demonstrated a significant (P < or = 0.05) increase in bone volume fraction and trabecular thickness. Overall trabecular orientation in the osteoarthritic group was more vertical or perpendicular to the articular surface than the control group (P < or = 0.05) especially in the trabeculae of the cancellous bone layer closest to the articular surface. These alterations in trabecular bone structure could have significant consequences for the mechanical properties of osteoarthritic bone.
ISSN:0171-967X
1432-0827
DOI:10.1007/BF00299000