A New Paclitaxel Photoaffinity Analog with a 3-(4-Benzoylphenyl)propanoyl Probe for Characterization of Drug-Binding Sites on Tubulin and P-Glycoprotein

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Bibliographic Details
Published in:Journal of medicinal chemistry 1995-09, Vol.38 (20), p.3891-3894
Main Authors: Ojima, Iwao, Duclos, Olivier, Dorman, Gyorgy, Simonot, Bruno, Prestwich, Glenn D, Rao, Srinivasa, Lerro, Keith A, Horwitz, Susan B
Format: Article
Language:English
Subjects:
Affinity Labels - metabolism
Animals
Antineoplastic agents
Antineoplastic Agents - metabolism
ATP Binding Cassette Transporter, Subfamily B, Member 1 - metabolism
Binding Sites
Biological and medical sciences
General aspects
Medical sciences
Mice
Paclitaxel - analogs & derivatives
Paclitaxel - metabolism
Pharmacology. Drug treatments
Taxoids
Tubulin - metabolism
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Description
Summary:
ISSN:0022-2623
1520-4804
DOI:10.1021/jm00020a001