DIFFERENTIAL EFFECTS OF ETHANOL ON THE PLASMA GLUCOSE OF NON-ALCOHOLIC LIGHT AND HEAVY SOCIAL DRINKERS

Plasma glucose levels (PGL) in healthy non-alcoholic heavy drinkers of both sexes were significantly higher than in light drinkers following feeding or fasting. Female heavy drinkers showed significant glucose intolerance following a standard (75 g) glucose tolerance test. Acute alcohol consumption...

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Bibliographic Details
Published in:Alcohol and alcoholism (Oxford) 1987, Vol.22 (1), p.23-29
Main Authors: CONNELLY, D. M., HARRIES, E. H. L., TABERNER, P. V.
Format: Article
Language:English
Subjects:
Adult
Alcohol Drinking - physiology
Blood Glucose - analysis
Ethanol - metabolism
Female
Glucose Tolerance Test
Humans
Kinetics
Male
Middle Aged
Saliva - metabolism
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Summary:Plasma glucose levels (PGL) in healthy non-alcoholic heavy drinkers of both sexes were significantly higher than in light drinkers following feeding or fasting. Female heavy drinkers showed significant glucose intolerance following a standard (75 g) glucose tolerance test. Acute alcohol consumption (0.4 g/kg orally) produced a larger fall in the PGL of heavy, compared with light, drinkers, although the rate of clearance of alcohol was similar in both groups. It is concluded that mild hyperglycaemia and glucose intolerance can occur in regular heavy drinkers who are otherwise clinically normal. It is suggested that previous drinking history is an important factor to be considered in assessing the metabolic response of non-alcoholics to acute alcohol consumption.
ISSN:0735-0414
1464-3502
1464-3502
DOI:10.1093/oxfordjournals.alcalc.a044660