Post-surgical deterioration of renal function in primary hyperoxaluria

Primary hyperoxaluria leading to calcium oxalate urinary stones and renal deposits occurs rarely in adults. We report three cases in whom end-stage renal failure was precipitated by urological surgery. In contrast, in one case renal stones were destroyed by extracorporeal shock-wave lithotripsy and...

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Published in:Nephrology, dialysis, transplantation dialysis, transplantation, 1987, Vol.1 (4), p.261-264
Main Authors: GRATEAU, G, GRÜNFELD, J. P, BEURTON, D, HANNEDOUCHE, T, CROSNIER, J
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Carbohydrates (enzymatic deficiencies). Glycogenosis
Errors of metabolism
Female
Humans
Hyperoxaluria - surgery
Hyperoxaluria, Primary - surgery
Kidney Calculi - surgery
Kidney Failure, Chronic - etiology
Male
Medical sciences
Metabolic diseases
Postoperative Complications - etiology
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Summary:Primary hyperoxaluria leading to calcium oxalate urinary stones and renal deposits occurs rarely in adults. We report three cases in whom end-stage renal failure was precipitated by urological surgery. In contrast, in one case renal stones were destroyed by extracorporeal shock-wave lithotripsy and renal function was not significantly altered. This emphasises the need for early diagnosis. This may not be easy in adult patients: urolithiasis may not be severe, radiological nephrocalcinosis may be lacking, and renal failure may develop late in life.
ISSN:0931-0509
1460-2385
1460-2385
DOI:10.1093/oxfordjournals.ndt.a091490