Nonproliferative diabetic retinopathy with significant capillary nonperfusion

A clinical study was carried out in 80 eyes of 50 diabetic patients with significant capillary nonperfusion at least in one eye. Panoramic photography of the fundus and wide-angle composite fluorescein angiography was performed in all cases. Forty-nine patients had type II diabetes. The mean age of...

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Bibliographic Details
Published in:Graefe's archive for clinical and experimental ophthalmology 1987-01, Vol.225 (3), p.157-159
Main Authors: VERDAGUER, J, LE CLERCQ, N, HOLUIGUE, J, MUSALEM, R
Format: Article
Language:English
Subjects:
Adult
Aged
Associated diseases and complications
Biological and medical sciences
Capillaries - physiopathology
Diabetes. Impaired glucose tolerance
Diabetic Retinopathy - pathology
Diabetic Retinopathy - physiopathology
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Fluorescein Angiography
Fundus Oculi
Humans
Iris - pathology
Medical sciences
Middle Aged
Regional Blood Flow
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Summary:A clinical study was carried out in 80 eyes of 50 diabetic patients with significant capillary nonperfusion at least in one eye. Panoramic photography of the fundus and wide-angle composite fluorescein angiography was performed in all cases. Forty-nine patients had type II diabetes. The mean age of the patients was 60 years and the mean duration of diabetes was 12.1 years; 46% of the patients had hypertensive vascular disease. Small neovascular tufts were observed in the iris sphincter in 20% of eyes. In addition, abnormal leakage of dye was observed in these eyes. Abnormal leakage of dye from the iris vessels was also observed in 9 of 20 eyes without clinically visible neovascularization. Numerous soft exudates distributed in a semicircular arc pattern were observed in 49% of eyes. Soft exudates were isolated and scarce in 37% of cases and were completely absent in 14% of eyes. Thus, in a substantial proportion of cases, the severity of the retinopathy could not be assessed by ophthalmoscopic findings alone.
ISSN:0721-832X
1435-702X
DOI:10.1007/BF02175440