A NEW ANTITUMOR ANTIBIOTIC, FR-900482: I. TAXONOMIC STUDIES ON THE PRODUCING STRAIN: A NEW SPECIES OF THE GENUS STREPTOMYCES

A new species in the genus Streptomyces, for which the name Streptomyces sandaensis sp. nov. is proposed, is described. Soil isolate strain No. 6897 (FERM-P 7654), produces a new antitumor substance FR-900482. The strain has a gray to red spore mass color, Rectus Flexibilis to Retinaculum-Apertum sp...

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Bibliographic Details
Published in:Journal of antibiotics 1987/05/25, Vol.40(5), pp.589-593
Main Authors: IWAMI, MORITA, KIYOTO, SUMIO, TERANO, HIROSHI, KOHSAKA, MASANOBU, AOKI, HATSUO, IMANAKA, HIROSHI
Format: Article
Language:English
Subjects:
Antibiotics, Antineoplastic - analysis
Antiviral drugs
Biological and medical sciences
Biotechnology
Bridged Bicyclo Compounds - analysis
Carbon - metabolism
Cell Wall - analysis
Culture Media
Fundamental and applied biological sciences. Psychology
Health. Pharmaceutical industry
Industrial applications and implications. Economical aspects
Oxazines
Production of active biomolecules
Soil Microbiology
Spores, Bacterial - analysis
Streptomyces - analysis
Streptomyces - classification
Streptomyces - physiology
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Summary:A new species in the genus Streptomyces, for which the name Streptomyces sandaensis sp. nov. is proposed, is described. Soil isolate strain No. 6897 (FERM-P 7654), produces a new antitumor substance FR-900482. The strain has a gray to red spore mass color, Rectus Flexibilis to Retinaculum-Apertum spore chain morphology, smooth spores, and is nonchromogenic. Strain No. 6897 is closely related to Streptomyces aburaviensis and Streptomyces nitrosporeus. But, there are many differences in cultural characteristics and in the utilization of carbohydrates.
ISSN:0021-8820
1881-1469
DOI:10.7164/antibiotics.40.589