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A NEW ANTITUMOR ANTIBIOTIC, FR-900482: I. TAXONOMIC STUDIES ON THE PRODUCING STRAIN: A NEW SPECIES OF THE GENUS STREPTOMYCES
A new species in the genus Streptomyces, for which the name Streptomyces sandaensis sp. nov. is proposed, is described. Soil isolate strain No. 6897 (FERM-P 7654), produces a new antitumor substance FR-900482. The strain has a gray to red spore mass color, Rectus Flexibilis to Retinaculum-Apertum sp...
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Published in: | Journal of antibiotics 1987/05/25, Vol.40(5), pp.589-593 |
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container_issue | 5 |
container_start_page | 589 |
container_title | Journal of antibiotics |
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creator | IWAMI, MORITA KIYOTO, SUMIO TERANO, HIROSHI KOHSAKA, MASANOBU AOKI, HATSUO IMANAKA, HIROSHI |
description | A new species in the genus Streptomyces, for which the name Streptomyces sandaensis sp. nov. is proposed, is described. Soil isolate strain No. 6897 (FERM-P 7654), produces a new antitumor substance FR-900482. The strain has a gray to red spore mass color, Rectus Flexibilis to Retinaculum-Apertum spore chain morphology, smooth spores, and is nonchromogenic. Strain No. 6897 is closely related to Streptomyces aburaviensis and Streptomyces nitrosporeus. But, there are many differences in cultural characteristics and in the utilization of carbohydrates. |
doi_str_mv | 10.7164/antibiotics.40.589 |
format | article |
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TAXONOMIC STUDIES ON THE PRODUCING STRAIN: A NEW SPECIES OF THE GENUS STREPTOMYCES</title><title>Journal of antibiotics</title><addtitle>J. Antibiot.</addtitle><description>A new species in the genus Streptomyces, for which the name Streptomyces sandaensis sp. nov. is proposed, is described. Soil isolate strain No. 6897 (FERM-P 7654), produces a new antitumor substance FR-900482. The strain has a gray to red spore mass color, Rectus Flexibilis to Retinaculum-Apertum spore chain morphology, smooth spores, and is nonchromogenic. Strain No. 6897 is closely related to Streptomyces aburaviensis and Streptomyces nitrosporeus. But, there are many differences in cultural characteristics and in the utilization of carbohydrates.</description><subject>Antibiotics, Antineoplastic - analysis</subject><subject>Antiviral drugs</subject><subject>Biological and medical sciences</subject><subject>Biotechnology</subject><subject>Bridged Bicyclo Compounds - analysis</subject><subject>Carbon - metabolism</subject><subject>Cell Wall - analysis</subject><subject>Culture Media</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Health. Pharmaceutical industry</subject><subject>Industrial applications and implications. Economical aspects</subject><subject>Oxazines</subject><subject>Production of active biomolecules</subject><subject>Soil Microbiology</subject><subject>Spores, Bacterial - analysis</subject><subject>Streptomyces - analysis</subject><subject>Streptomyces - classification</subject><subject>Streptomyces - physiology</subject><issn>0021-8820</issn><issn>1881-1469</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><recordid>eNpNkE9PwkAQxTdGg4h-ARMTDurJ4uy_7u4RCWgjQkJKPG62y6IlpcVuOfjtrdA0XGYmeb-ZN3kI3WIYCByyZ5NXaZIWVWr9gMGAS3WGulhKHGAWqnPUBSA4kJLAJbryfgNABRWygzo0xCCx6KKHYX82_uwPZ3EULz_mi8P0Es3jaPTUnywCBcAkuUYXa5N5d9P0HlpOxvHoLZjOX6PRcBpYRkAFAjgOqeNcYEWNCo0RsJYrxuqfuJU8oQqsxZTShHLFDeVCrZxJiBSOg-K0hx6Pd3dl8bN3vtLb1FuXZSZ3xd5rIUICjIc1SI6gLQvvS7fWuzLdmvJXY9D_2eiTbDQDXWdTL9011_fJ1q3alSaMWr9vdOOtydalyW3qW0wSoqgiNfZ-xDa-Ml-u1U1Zm2Xu1BmrUB7cj6V-oqXstym1y-kfr9yDqg</recordid><startdate>1987</startdate><enddate>1987</enddate><creator>IWAMI, MORITA</creator><creator>KIYOTO, SUMIO</creator><creator>TERANO, HIROSHI</creator><creator>KOHSAKA, MASANOBU</creator><creator>AOKI, HATSUO</creator><creator>IMANAKA, HIROSHI</creator><general>JAPAN ANTIBIOTICS RESEARCH ASSOCIATION</general><general>Japan Antibiotics Research Association</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1987</creationdate><title>A NEW ANTITUMOR ANTIBIOTIC, FR-900482</title><author>IWAMI, MORITA ; KIYOTO, SUMIO ; TERANO, HIROSHI ; KOHSAKA, MASANOBU ; AOKI, HATSUO ; IMANAKA, HIROSHI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4209-705163e557193a96aa70f8d441885c85b390cc1333b3595a3579deab287e50953</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1987</creationdate><topic>Antibiotics, Antineoplastic - analysis</topic><topic>Antiviral drugs</topic><topic>Biological and medical sciences</topic><topic>Biotechnology</topic><topic>Bridged Bicyclo Compounds - analysis</topic><topic>Carbon - metabolism</topic><topic>Cell Wall - analysis</topic><topic>Culture Media</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Health. Pharmaceutical industry</topic><topic>Industrial applications and implications. Economical aspects</topic><topic>Oxazines</topic><topic>Production of active biomolecules</topic><topic>Soil Microbiology</topic><topic>Spores, Bacterial - analysis</topic><topic>Streptomyces - analysis</topic><topic>Streptomyces - classification</topic><topic>Streptomyces - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>IWAMI, MORITA</creatorcontrib><creatorcontrib>KIYOTO, SUMIO</creatorcontrib><creatorcontrib>TERANO, HIROSHI</creatorcontrib><creatorcontrib>KOHSAKA, MASANOBU</creatorcontrib><creatorcontrib>AOKI, HATSUO</creatorcontrib><creatorcontrib>IMANAKA, HIROSHI</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of antibiotics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>IWAMI, MORITA</au><au>KIYOTO, SUMIO</au><au>TERANO, HIROSHI</au><au>KOHSAKA, MASANOBU</au><au>AOKI, HATSUO</au><au>IMANAKA, HIROSHI</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A NEW ANTITUMOR ANTIBIOTIC, FR-900482: I. TAXONOMIC STUDIES ON THE PRODUCING STRAIN: A NEW SPECIES OF THE GENUS STREPTOMYCES</atitle><jtitle>Journal of antibiotics</jtitle><addtitle>J. Antibiot.</addtitle><date>1987</date><risdate>1987</risdate><volume>40</volume><issue>5</issue><spage>589</spage><epage>593</epage><pages>589-593</pages><issn>0021-8820</issn><eissn>1881-1469</eissn><coden>JANTAJ</coden><abstract>A new species in the genus Streptomyces, for which the name Streptomyces sandaensis sp. nov. is proposed, is described. Soil isolate strain No. 6897 (FERM-P 7654), produces a new antitumor substance FR-900482. The strain has a gray to red spore mass color, Rectus Flexibilis to Retinaculum-Apertum spore chain morphology, smooth spores, and is nonchromogenic. Strain No. 6897 is closely related to Streptomyces aburaviensis and Streptomyces nitrosporeus. 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subjects | Antibiotics, Antineoplastic - analysis Antiviral drugs Biological and medical sciences Biotechnology Bridged Bicyclo Compounds - analysis Carbon - metabolism Cell Wall - analysis Culture Media Fundamental and applied biological sciences. Psychology Health. Pharmaceutical industry Industrial applications and implications. Economical aspects Oxazines Production of active biomolecules Soil Microbiology Spores, Bacterial - analysis Streptomyces - analysis Streptomyces - classification Streptomyces - physiology |
title | A NEW ANTITUMOR ANTIBIOTIC, FR-900482: I. TAXONOMIC STUDIES ON THE PRODUCING STRAIN: A NEW SPECIES OF THE GENUS STREPTOMYCES |
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