Bleomycin sclerotherapy in patients with congenital lymphatic malformation in the head and neck

Congenital lymphatic malformations of the head and neck often present challenging problems to the otolaryngologist-head and neck surgeon. Although surgical excision was agreed to be the treatment of choice for this disease, the infiltrating nature of lymphatic channels often increases the frequency...

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Bibliographic Details
Published in:American Journal of Otolaryngology--Head and Neck Medicine and Surgery 1995-07, Vol.16 (4), p.236-241
Main Authors: Sung, Myung-Whun, Chang, Sun O., Choi, Joong Hwan, Kim, Jin Young
Format: Article
Language:English
Subjects:
Antineoplastic Agents - therapeutic use
Biological and medical sciences
Bleomycin - therapeutic use
Child
Female
Head - pathology
Head and Neck Neoplasms - congenital
Head and Neck Neoplasms - drug therapy
Head and Neck Neoplasms - pathology
Hemangioma - congenital
Hemangioma - drug therapy
Hemangioma - pathology
Humans
Infant, Newborn
Male
Medical sciences
Neck - pathology
Non tumoral diseases
Otorhinolaryngology (head neck, general aspects and miscellaneous)
Otorhinolaryngology. Stomatology
Sclerotherapy
Treatment Outcome
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Summary:Congenital lymphatic malformations of the head and neck often present challenging problems to the otolaryngologist-head and neck surgeon. Although surgical excision was agreed to be the treatment of choice for this disease, the infiltrating nature of lymphatic channels often increases the frequency of operative complications and recurrences of this lesion. Purpose: Bleomycin sclerotherapy was attempted to avoid surgical risk and to cure this lesion. Materials and Methods: Clinical findings and treatment results were reviewed for patients with congenital lymphatic malformation and treated by bleomycin sclerotherapy. Results: Bleomycin sclerotherapy was a very effective therapeutic alternative. The best results were seen in cystic type I lesions in younger patients. Conclusions: Bleomycin sclerotherapy is a useful medical alternative, and we believe that it should be attempted before excision of the lesion.
ISSN:0196-0709
1532-818X
DOI:10.1016/0196-0709(95)90149-3