Haemoglobin analysis by capillary zone electrophoresis

The analysis of haemoglobin is routine in medical laboratories for the purpose of assessing blood disorders and related pathologies. Haemoglobin is structurally diverse and possesses many variant forms, some disease-producing. With recent improvements in technology, capillary electrophoresis is now...

Full description

Saved in:
Bibliographic Details
Published in:Journal of Chromatography A 1995-08, Vol.709 (1), p.121-125
Main Authors: Şahin, Ahmet, Laleli, Yahya R., Ortancil, Recep
Format: Article
Language:English
Subjects:
Buffers
Electrophoresis - methods
Hemoglobins - analysis
Humans
Hydrogen-Ion Concentration
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The analysis of haemoglobin is routine in medical laboratories for the purpose of assessing blood disorders and related pathologies. Haemoglobin is structurally diverse and possesses many variant forms, some disease-producing. With recent improvements in technology, capillary electrophoresis is now being adapted in the clinical laboratory. This paper describes the analysis of haemoglobin variants using uncoated fused-silica capillaries. The effects of using different buffer salts at different concentrations with different buffer pH values to separate haemoglobin variants in these capillaries are described.
ISSN:0021-9673
DOI:10.1016/0021-9673(95)00229-G