Vaccination with Anaplasma centrale: response after an experimental challenge with Anaplasma marginale

The haematological and clinical responses to vaccination with Anaplasma centrale and to subsequent challenge with Anaplasma marginale were evaluated. Twenty Holstein steers 14 to 16 months of age were divided into two groups of 12 and eight animals respectively (groups I and II). Group I was inocula...

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Bibliographic Details
Published in:Tropical animal health and production 1987-05, Vol.19 (2), p.83-87
Main Authors: Anziani, O.S, Tarabla, H.D, Ford, C.A, Galleto, C
Format: Article
Language:English
Subjects:
Anaplasma - immunology
Anaplasma centrale
Anaplasma marginale
anaplasmosis
Anaplasmosis - blood
Anaplasmosis - immunology
Animals
Bacterial Vaccines - adverse effects
Bacterial Vaccines - immunology
Body Temperature
Cattle
Cattle Diseases - blood
Cattle Diseases - immunology
Hematocrit - veterinary
Male
pathogenicity
steers
vaccination
Vaccination - veterinary
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Summary:The haematological and clinical responses to vaccination with Anaplasma centrale and to subsequent challenge with Anaplasma marginale were evaluated. Twenty Holstein steers 14 to 16 months of age were divided into two groups of 12 and eight animals respectively (groups I and II). Group I was inoculated on day zero with 10(7) A. centrale-infected erythrocytes and group II was kept as a control. On day 125 both groups were challenged with 5 X 10(7) A. marginale-infected erythrocytes. A. centrale inoculation produced low parasitaemias (maximum mean 2.7%), moderate packed cell volume (PCV) falls (minimum mean 20.5%) and no clinical symptoms. After the challenge group I had significantly lower parasitaemia (maximum mean 2.3%) and higher PCV (minimum mean 20.1%) than group II (7.5% and 14.5% respectively). Four steers from group II developed acute anaplasmosis and required treatment.
ISSN:0049-4747
1573-7438
DOI:10.1007/BF02297324