Protein-tyrosine phosphatase SH-PTP2 (PTPN11) is localized to 12q24.1-24.3

A 2.1-kb cDNA probe encoding the human SH2-domain containing protein-tyrosine phosphatase SH-PTP2 (PTPN11) was hybridized to human metaphase chromosomes in three independent experiments. In each instance, hybridization was maximal to chromosome 12q24.1-q24.3. The presence of SH-PTP2 cDNA crosshybrid...

Full description

Saved in:
Bibliographic Details
Published in:Human genetics 1995-11, Vol.96 (5), p.609-615
Main Authors: DECHERT, U, DUNCAN, A. M. V, BASTIEN, L, DUFF, C, MOHAMMED ADAM, JIRIK, F. R
Format: Article
Language:English
Subjects:
Biological and medical sciences
Chromosome Mapping
Chromosomes, Human, Pair 12 - genetics
Classical genetics, quantitative genetics, hybrids
DNA Probes
Fundamental and applied biological sciences. Psychology
Genetics of eukaryotes. Biological and molecular evolution
Human
Humans
In Situ Hybridization
Intracellular Signaling Peptides and Proteins
Protein Tyrosine Phosphatase, Non-Receptor Type 11
Protein Tyrosine Phosphatase, Non-Receptor Type 6
Protein Tyrosine Phosphatases - genetics
SH2 Domain-Containing Protein Tyrosine Phosphatases
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A 2.1-kb cDNA probe encoding the human SH2-domain containing protein-tyrosine phosphatase SH-PTP2 (PTPN11) was hybridized to human metaphase chromosomes in three independent experiments. In each instance, hybridization was maximal to chromosome 12q24.1-q24.3. The presence of SH-PTP2 cDNA crosshybridizing sequences located on a number of other chromosomes suggested that SH-PTP2-related genes or pseudogenes are present in the human genome.
ISSN:0340-6717
1432-1203
DOI:10.1007/BF00197421