Alveolar capillary dysplasia--a cause of persistent pulmonary hypertension unresponsive to a second course of extracorporeal membrane oxygenation

Recurrence of persistent pulmonary hypertension of the newborn (PPHN) after successful extracorporeal membrane oxygenation (ECMO) therapy has been reported.1,2 Payne1 treated the recurrence of PPHN with conventional therapy, and two of his three patients recovered. De La Cruz2 reported using a secon...

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Bibliographic Details
Published in:Pediatrics (Evanston) 1995-12, Vol.96 (6), p.1159-1161
Main Authors: Chelliah, B P, Brown, D, Cohen, M, Talleyrand, A J, Shen-Schwarz, S
Format: Article
Language:English
Subjects:
Abnormalities, Multiple - pathology
Babies
Capillaries - abnormalities
Extracorporeal Membrane Oxygenation
Fatal Outcome
Humans
Hypertension
Infant, Newborn
Lungs
Male
Medical research
Oxygen
Pediatrics
Persistent Fetal Circulation Syndrome - etiology
Persistent Fetal Circulation Syndrome - pathology
Persistent Fetal Circulation Syndrome - therapy
Pulmonary Alveoli - blood supply
Pulmonary Alveoli - pathology
Respiratory diseases
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Summary:Recurrence of persistent pulmonary hypertension of the newborn (PPHN) after successful extracorporeal membrane oxygenation (ECMO) therapy has been reported.1,2 Payne1 treated the recurrence of PPHN with conventional therapy, and two of his three patients recovered. De La Cruz2 reported using a second course of ECMO to treat a recurrence of pulmonary hypertension and respiratory failure of other origins in three patients. Two of the three infants survived. As of January 13, 1993, there were a total of 47 infants reported to the Extracorporeal Life Support Organization (ELSO) who had undergone a second course of ECMO.3 The two most common diagnoses among these infants were congenital diaphragrnatic hernia and PPHN.
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.96.6.1159